Pathophysiology of early brain injury and its association with delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage: a review of current literature

DL Alsbrook, M Di Napoli, K Bhatia, M Desai… - Journal of Clinical …, 2023 - mdpi.com
Background: Delayed cerebral ischemia (DCI) is a common and serious complication of
aneurysmal subarachnoid hemorrhage (aSAH). Though many clinical trials have looked at …

Thrombocytopathies: not just aggregation defects—the clinical relevance of procoagulant platelets

A Aliotta, D Bertaggia Calderara, MG Zermatten… - Journal of clinical …, 2021 - mdpi.com
Platelets are active key players in haemostasis. Qualitative platelet dysfunctions result in
thrombocytopathies variously characterized by defects of their adhesive and procoagulant …

A 90-day prognostic model based on the early brain injury indicators after aneurysmal subarachnoid hemorrhage: the TAPS score

R Li, F Lin, Y Chen, J Lu, H Han, L Ma, Y Zhao… - Translational Stroke …, 2023 - Springer
This study aimed to establish a new scoring model based on the early brain injury (EBI)
indicators to predict the 90-day functional outcomes in patients with aneurysmal …

Role of platelets in the pathogenesis of delayed injury after subarachnoid hemorrhage

A Dienel, P Kumar T, SL Blackburn… - Journal of Cerebral …, 2021 - journals.sagepub.com
Aneurysmal subarachnoid hemorrhage (aSAH) patients develop delayed cerebral ischemia
and delayed deficits (DCI) within 2 weeks of aneurysm rupture at a rate of approximately …

[HTML][HTML] Procoagulant platelets: mechanisms of generation and action

NA Podoplelova, DY Nechipurenko… - …, 2021 - thieme-connect.com
During the past decades, it has been increasingly recognized that the major function of
accelerating membrane-dependent reactions of blood coagulation is predominantly …

Inflammation: a good research target to improve outcomes of poor-grade subarachnoid hemorrhage

H Suzuki - Translational Stroke Research, 2019 - Springer
Aneurysmal subarachnoid hemorrhage (SAH) remains a devastating cerebrovascular
disease [1] and should be treated as a systemic disorder needing intensive care, not merely …

Systemic response of coated-platelet and peripheral blood inflammatory cell indices after aneurysmal subarachnoid hemorrhage and long-term clinical outcome

B Ray, SR Ross, G Danala, F Aghaei, CD Nouh… - Journal of critical …, 2019 - Elsevier
Purpose Post-hemorrhage period after aneurysmal subarachnoid hemorrhage (aSAH) has
several systemic manifestations including prothrombotic and pro-inflammatory states. Inter …

Applying quantitative radiographic image markers to predict clinical complications after aneurysmal subarachnoid hemorrhage: A pilot study

G Danala, M Desai, B Ray, M Heidari… - Annals of biomedical …, 2022 - Springer
Accurately predicting clinical outcome of aneurysmal subarachnoid hemorrhage (aSAH)
patients is difficult. The purpose of this study was to develop and test a new fully-automated …

Acute platelet response to aneurysmal subarachnoid hemorrhage depends on severity and distribution of bleeding: an observational cohort study

R Rzepliński, K Kostyra, T Skadorwa, M Sługocki… - Neurosurgical …, 2021 - Springer
Microthrombosis after aneurysmal subarachnoid hemorrhage (aSAH) is considered to
initiate neuroinflammation, vessel remodeling, and blood-brain barrier leakage. We aimed to …

Thromboelastometry shows early hypercoagulation in patients with spontaneous subarachnoid hemorrhage

SV Lauridsen, CL Hvas, E Sandgaard, T Gyldenholm… - World neurosurgery, 2019 - Elsevier
Background The ability to achieve hemostasis after spontaneous subarachnoid hemorrhage
(SAH) plays a pivotal role in outcome. Changes in coagulation in the early hours after SAH …