The Many Hosts of Mycobacteria 9 (MHM9): A conference report

AM Klever, K Alexander, D Almeida, MZ Anderson… - Tuberculosis, 2023 - Elsevier
Abstract The Many Hosts of Mycobacteria (MHM) meeting series brings together basic
scientists, clinicians and veterinarians to promote robust discussion and dissemination of …

[HTML][HTML] Attention2majority: Weak multiple instance learning for regenerative kidney grading on whole slide images

Z Su, TE Tavolara, G Carreno-Galeano, SJ Lee… - Medical Image …, 2022 - Elsevier
Deep learning consistently demonstrates high performance in classifying and segmenting
medical images like CT, PET, and MRI. However, compared to these kinds of images, whole …

Deep weakly-supervised learning methods for classification and localization in histology images: a survey

J Rony, S Belharbi, J Dolz, IB Ayed, L McCaffrey… - arXiv preprint arXiv …, 2019 - arxiv.org
Using deep learning models to diagnose cancer from histology data presents several
challenges. Cancer grading and localization of regions of interest (ROIs) in these images …

Contrastive multiple instance learning: An unsupervised framework for learning slide-level representations of whole slide histopathology images without labels

TE Tavolara, MN Gurcan, MKK Niazi - Cancers, 2022 - mdpi.com
Simple Summary Recent AI methods in the automated analysis of histopathological imaging
data associated with cancer have trended towards less supervision by humans. Yet, there …

Immunological roads diverged: mapping tuberculosis outcomes in mice

RK Meade, CM Smith - Trends in Microbiology, 2024 - cell.com
The journey from phenotypic observation to causal genetic mechanism is a long and
challenging road. For pathogens like Mycobacterium tuberculosis (Mtb), which causes …

CXCL1: A new diagnostic biomarker for human tuberculosis discovered using Diversity Outbred mice

D Koyuncu, MKK Niazi, T Tavolara, C Abeijon… - PLoS …, 2021 - journals.plos.org
More humans have died of tuberculosis (TB) than any other infectious disease and millions
still die each year. Experts advocate for blood-based, serum protein biomarkers to help …

BCR-Net: A deep learning framework to predict breast cancer recurrence from histopathology images

Z Su, MKK Niazi, TE Tavolara, S Niu, GH Tozbikian… - Plos one, 2023 - journals.plos.org
Breast cancer is the most common malignancy in women, with over 40,000 deaths annually
in the United States alone. Clinicians often rely on the breast cancer recurrence score …

Deep learning predicts gene expression as an intermediate data modality to identify susceptibility patterns in Mycobacterium tuberculosis infected Diversity Outbred …

TE Tavolara, MKK Niazi, AC Gower, M Ginese… - …, 2021 - thelancet.com
Background Machine learning sustains successful application to many diagnostic and
prognostic problems in computational histopathology. Yet, few efforts have been made to …

Systems genetics uncover new loci containing functional gene candidates in Mycobacterium tuberculosis-infected Diversity Outbred mice

DM Gatti, AL Tyler, JM Mahoney, GA Churchill… - PLoS …, 2024 - journals.plos.org
Mycobacterium tuberculosis infects two billion people across the globe, and results in 8–9
million new tuberculosis (TB) cases and 1–1.5 million deaths each year. Most patients have …

Prediction of Tuberculosis From Lung Tissue Images of Diversity Outbred Mice Using Jump Knowledge Based Cell Graph Neural Network

V Acharya, D Choi, B Yener, G Beamer - IEEE Access, 2024 - ieeexplore.ieee.org
Tuberculosis (TB), primarily affecting the lungs, is caused by the bacterium Mycobacterium
tuberculosis and poses a significant health risk. Detecting acid-fast bacilli (AFB) in stained …