Reperfusion of the heart after a period of ischaemia leads to the opening of a nonspecific
pore in the inner mitochondrial membrane, known as the mitochondrial permeability …

Acute ischemic stroke is a critical condition that can result in disability and death. The
consequences of this medical condition depend on various factors, including the size of the …

Excessive heat exposure reduces intestinal integrity and post-absorptive energetics that can
inhibit wellbeing and be fatal. Therefore, our objectives were to examine how acute heat …

Heat stress can compromise intestinal integrity and induce leaky gut in a variety of species.
Therefore, the objectives of this study were to determine if heat stress (HS) directly or …

The transmembrane sodium gradient is essential for both excitability of the cardiac cell and
the regulation of the cytoplasmic concentrations of Ca and protons. In addition, movements …

BACKGROUND: The mechanisms underlying heart failure induced by adriamycin are very
complicated and still unclear. The aim of this study was to investigate whether autophagy …

The current standard of care for acute myocardial infarction or 'heart attack'is timely
restoration of blood flow to the ischemic region of the heart. While reperfusion is essential for …

Na, K-ATPase is highly sensitive to changes in the redox state, and yet the mechanisms of
its redox sensitivity remain unclear. We have explored the possible involvement of S …

Control over the Na, K-ATPase function plays a central role in adaptation of the organisms to
hypoxic and anoxic conditions. As the enzyme itself does not possess O2 binding sites its …

Acute myocardial ischemia is one of the main causes of sudden cardiac death. The
mechanisms have been investigated primarily in experimental and computational studies …