Astrocyte function from information processing to cognition and cognitive impairment
Astrocytes serve important roles that affect recruitment and function of neurons at the local
and network levels. Here we review the contributions of astrocyte signaling to synaptic …
and network levels. Here we review the contributions of astrocyte signaling to synaptic …
Physiology of astroglia
A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
[HTML][HTML] Astrocytic activation generates de novo neuronal potentiation and memory enhancement
Astrocytes respond to neuronal activity and were shown to be necessary for plasticity and
memory. To test whether astrocytic activity is also sufficient to generate synaptic potentiation …
memory. To test whether astrocytic activity is also sufficient to generate synaptic potentiation …
Bidirectional microglia–neuron communication in health and disease
Z Szepesi, O Manouchehrian, S Bachiller… - Frontiers in cellular …, 2018 - frontiersin.org
Microglia are ramified cells that exhibit highly motile processes, which continuously survey
the brain parenchyma and react to any insult to the CNS homeostasis. Although microglia …
the brain parenchyma and react to any insult to the CNS homeostasis. Although microglia …
The role of cytokines in modulating learning and memory and brain plasticity
JM Bourgognon, J Cavanagh - Brain and neuroscience …, 2020 - journals.sagepub.com
Cytokines are proteins secreted in the central nervous system by neurons, microglia,
astrocytes and infiltrating peripheral immune cells under physiological and pathological …
astrocytes and infiltrating peripheral immune cells under physiological and pathological …
Neuronal hyperexcitability in Alzheimer's disease: what are the drivers behind this aberrant phenotype?
Alzheimer's disease (AD) is a progressive neurodegenerative disorder leading to loss of
cognitive abilities and ultimately, death. With no cure available, limited treatments mostly …
cognitive abilities and ultimately, death. With no cure available, limited treatments mostly …
Astrocyte calcium signaling: the third wave
N Bazargani, D Attwell - Nature neuroscience, 2016 - nature.com
The discovery that transient elevations of calcium concentration occur in astrocytes, and
release'gliotransmitters' which act on neurons and vascular smooth muscle, led to the idea …
release'gliotransmitters' which act on neurons and vascular smooth muscle, led to the idea …
Diversity and specificity of astrocyte–neuron communication
CA Durkee, A Araque - Neuroscience, 2019 - Elsevier
Astrocytes are emerging as important players in synaptic function, and, consequently, on
brain function and animal behavior. According to the Tripartite Synapse concept, astrocytes …
brain function and animal behavior. According to the Tripartite Synapse concept, astrocytes …
Inflammation, glutamate, and glia: a trio of trouble in mood disorders
Increasing data indicate that inflammation and alterations in glutamate neurotransmission
are two novel pathways to pathophysiology in mood disorders. The primary goal of this …
are two novel pathways to pathophysiology in mood disorders. The primary goal of this …
Gliotransmission: beyond black-and-white
I Savtchouk, A Volterra - Journal of Neuroscience, 2018 - Soc Neuroscience
Astrocytes are highly complex cells with many emerging putative roles in brain function. Of
these, gliotransmission (active information transfer from glia to neurons) has probably the …
these, gliotransmission (active information transfer from glia to neurons) has probably the …