Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies

M Solmi, M De Toffol, JY Kim, MJ Choi, B Stubbs… - bmj, 2023 - bmj.com
Objective To systematically assess credibility and certainty of associations between
cannabis, cannabinoids, and cannabis based medicines and human health, from …

Cannabidiol: pharmacology and therapeutic targets

SC Britch, S Babalonis, SL Walsh - Psychopharmacology, 2021 - Springer
Rationale Cannabidiol (CBD) products lacking regulatory approval are being used to self-
treat a myriad of conditions and for their unsubstantiated health benefits. The scientific …

[HTML][HTML] Lower-Risk Cannabis Use Guidelines (LRCUG) for reducing health harms from non-medical cannabis use: A comprehensive evidence and recommendations …

B Fischer, T Robinson, C Bullen, V Curran… - International Journal of …, 2022 - Elsevier
Background Cannabis use is common, especially among young people, and is associated
with risks for various health harms. Some jurisdictions have recently moved to …

Reasons for cannabidiol use: a cross-sectional study of CBD users, focusing on self-perceived stress, anxiety, and sleep problems

J Moltke, C Hindocha - Journal of cannabis research, 2021 - Springer
Background Public and medical interest in cannabidiol (CBD) has been rising, and CBD is
now available from various sources. Research into the effects of low-dose CBD on outcomes …

Towards better delivery of cannabidiol (CBD)

SA Millar, RF Maguire, AS Yates, SE O'Sullivan - Pharmaceuticals, 2020 - mdpi.com
Cannabidiol (CBD) has substantial therapeutic potential, but its development as an effective
drug by the pharmaceutical industry is hindered by intrinsic characteristics such as low …

Psychobehavioural and cognitive adverse events of anti-seizure medications for the treatment of developmental and epileptic encephalopathies

A Strzelczyk, S Schubert-Bast - CNS drugs, 2022 - Springer
The developmental and epileptic encephalopathies encompass a group of rare syndromes
characterised by severe drug-resistant epilepsy with onset in childhood and significant …

Cannabis sativa L. Bioactive Compounds and Their Protective Role in Oxidative Stress and Inflammation

DM Kopustinskiene, R Masteikova, R Lazauskas… - Antioxidants, 2022 - mdpi.com
Cannabis (Cannabis sativa L.) plants from the family Cannabidaceae have been used since
ancient times, to produce fibers, oil, and for medicinal purposes. Psychoactive delta-9 …

Effect of cannabidiol and Δ9-tetrahydrocannabinol on driving performance: a randomized clinical trial

TR Arkell, F Vinckenbosch, RC Kevin, EL Theunissen… - Jama, 2020 - jamanetwork.com
Importance Cannabis use has been associated with increased crash risk, but the effect of
cannabidiol (CBD) on driving is unclear. Objective To determine the driving impairment …

Cannabidiol for the treatment of cannabis use disorder: a phase 2a, double-blind, placebo-controlled, randomised, adaptive Bayesian trial

TP Freeman, C Hindocha, G Baio… - The Lancet …, 2020 - thelancet.com
Background A substantial and unmet clinical need exists for pharmacological treatment of
cannabis use disorders. Cannabidiol could offer a novel treatment, but it is unclear which …

Cannabidiol treatment in hand osteoarthritis and psoriatic arthritis: a randomized, double-blind, placebo-controlled trial

J Vela, L Dreyer, KK Petersen, L Arendt-Nielsen… - Pain, 2022 - journals.lww.com
Cannabidiol (CBD) is increasingly used as analgesic medication although the recent
International Association for the Study of Pain Presidential Task Force on cannabis and …