Cellular activation pathways and interaction networks in vascularized composite allotransplantation

L Knoedler, S Knoedler, AC Panayi, CAA Lee… - Frontiers in …, 2023 - frontiersin.org
Vascularized composite allotransplantation (VCA) is an evolving field of reconstructive
surgery that has revolutionized the treatment of patients with devastating injuries, including …

Regulatory T cells in skin regeneration and wound healing

S Knoedler, L Knoedler, M Kauke-Navarro… - Military Medical …, 2023 - Springer
As the body's integumentary system, the skin is vulnerable to injuries. The subsequent
wound healing processes aim to restore dermal and epidermal integrity and functionality. To …

[HTML][HTML] Tolerance induction in vascularized composite allotransplantation—a brief review of preclinical models

L Huelsboemer, M Kauke-Navarro… - Transplant …, 2023 - frontierspartnerships.org
Pre-clinical studies are an obligatory tool to develop and translate novel therapeutic
strategies into clinical practice. Acute and chronic rejection mediated by the recipient's …

[HTML][HTML] International consensus recommendations on face transplantation: A 2-step Delphi study

B Longo, FB Alberti, B Pomahac, JJ Pribaz… - American Journal of …, 2024 - Elsevier
Face transplantation is a viable reconstructive approach for severe craniofacial defects.
Despite the evolution witnessed in the field, ethical aspects, clinical and psychosocial …

Application possibilities of artificial intelligence in facial vascularized composite allotransplantation—a narrative review

L Knoedler, S Knoedler, O Allam, K Remy… - Frontiers in …, 2023 - frontiersin.org
Facial vascularized composite allotransplantation (FVCA) is an emerging field of
reconstructive surgery that represents a dogmatic shift in the surgical treatment of patients …

Novel strategies in transplantation: genetic engineering and vascularized composite allotransplantation

M Kauke-Navarro, OF Noel, L Knoedler… - Journal of Surgical …, 2023 - Elsevier
Introduction Despite the clinical success in vascularized composite allotransplantation
(VCA), systemic immunosuppression remains necessary to prevent allograft rejection. Even …

Clinical and preclinical tolerance protocols for vascularized composite allograft transplantation

JH Yang, AC Johnson, S Colakoglu… - Archives of plastic …, 2021 - thieme-connect.com
The field of vascularized composite allografts (VCAs) has undergone significant
advancement in recent decades, and VCAs are increasingly common and accepted in the …

Regulatory T cells: liquid and living precision medicine for the future of VCA

M Kauke-Navarro, S Knoedler, AC Panayi… - …, 2023 - journals.lww.com
Transplant rejection remains a challenge especially in the field of vascularized composite
allotransplantation (VCA). To blunt the alloreactive immune response ‚stable levels of …

Measurements of motor functional outcomes in facial transplantation: A systematic review

D Boczar, RR Colon, ZP Berman, GK Diep… - Journal of Plastic …, 2022 - Elsevier
Although the ethical and technical feasibility of face transplant (FT) has been established,
current literature lacks consensus on functional outcomes monitoring for recipients. This …

Cytomegalovirus-related complications and management in facial vascularized composite allotransplantation: an international multicenter retrospective cohort study

M Kauke-Navarro, AC Panayi, R Formica, F Marty… - …, 2022 - journals.lww.com
Background. There is a paucity of data on the impact of cytomegalovirus (CMV) serostatus
and CMV infection on outcomes in facial vascularized composite allotransplantation …