Progress in the treatment of drug-induced liver injury with natural products

Y Sun, Y Zhang, L Xie, F Rong, X Zhu, J Xie… - Pharmacological …, 2022 - Elsevier
There are numerous prescription drugs and non-prescription drugs that cause drug-induced
liver injury (DILI), which is the main cause of liver disease in humans around the globe. Its …

Role and mechanisms of autophagy in acetaminophen‐induced liver injury

X Chao, H Wang, H Jaeschke, WX Ding - Liver International, 2018 - Wiley Online Library
Acetaminophen (APAP) overdose is the most frequent cause of acute liver failure in the USA
and many other countries. Although the metabolism and pathogenesis of APAP has been …

Oral paracetamol (acetaminophen) for cancer pain

PJ Wiffen, S Derry, RA Moore… - Cochrane Database …, 2017 - cochranelibrary.com
Background Pain is a common symptom with cancer, and 30% to 50% of all people with
cancer will experience moderate to severe pain that can have a major negative impact on …

Acetaminophen-induced acute liver failure is more common and more severe in women

JB Rubin, B Hameed, M Gottfried, WM Lee… - Clinical …, 2018 - Elsevier
Background & Aims Acetaminophen overdose is the leading cause of acute liver injury (ALI)
and acute liver failure (ALF) in the developed world. Sex differences in acetaminophen …

Novel treatment of acute and acute‐on‐chronic liver failure: interleukin‐22

S Hwang, A Hicks, CZ Hoo, YS Kwon, YE Cho… - Liver …, 2023 - Wiley Online Library
Acute liver failure (ALF) is a life‐threatening medical condition, characterized by rapidly
progressive hepatic dysfunction, coagulopathy and hepatic encephalopathy in patients …

Sestrin2 protects against acetaminophen-induced liver injury

SJ Kim, KM Kim, JH Yang, SS Cho, JY Kim… - Chemico-biological …, 2017 - Elsevier
Acetaminophen (APAP) overdose accounts for half of the cases of acute liver failure
worldwide. We previously reported that Sestrin2 (Sesn2) protects against d-galactosamine …

Nationwide trends of clinical characteristics and economic burden of emergency department visits due to acute ischemic stroke

M Stuntz, K Busko, S Irshad, T Paige… - Open Access …, 2017 - Taylor & Francis
We aimed to provide estimates of the volume and associated charges of acute ischemic
stroke (AIS) visits in the US, as well as to assess predictors of patient disposition following …

Circulating acetaminophen metabolites are toxicokinetic biomarkers of acute liver injury

ADB Vliegenthart, RA Kimmitt… - Clinical …, 2017 - Wiley Online Library
Acetaminophen (paracetamol‐APAP) is the most common cause of drug‐induced liver injury
in the Western world. Reactive metabolite production by cytochrome P450 enzymes (CYP …

A comparison of transdermal over-the-counter lidocaine 3.6% menthol 1.25%, Rx lidocaine 5% and placebo for back pain and arthritis

E Castro, D Dent - Pain management, 2017 - Taylor & Francis
Aim: Transdermal lidocaine therapy has become a gold standard as part of a treatment
regimen for patients who suffer from localized pain. We compared transdermal patches: over …

Goji Ferment Ameliorated Acetaminophen-Induced Liver Injury in vitro and in vivo

CM Yang, MY Chien, LY Wang, CH Chuang… - Probiotics and …, 2023 - Springer
This study aimed to investigate the hepatoprotective effects of lyophilized powder of goji
ferment (LPGF) against acetaminophen (APAP)-induced hepatic damage in Hep3B cells …