Mouse social stress induces increased fear conditioning, helplessness and fatigue to physical challenge together with markers of altered immune and dopamine …
D Azzinnari, H Sigrist, S Staehli, R Palme… - …, 2014 - Elsevier
In neuropsychiatry, animal studies demonstrating causal effects of environmental
manipulations relevant to human aetiology on behaviours relevant to human …
manipulations relevant to human aetiology on behaviours relevant to human …
Sequence variants associated with resilient responses in growing pigs
H Laghouaouta, M Laplana… - Journal of Animal …, 2024 - Wiley Online Library
The current work aimed to identify genomic regions and candidate genes associated with
resilience in pigs. In previous work, we proposed the body weight deviation from the …
resilience in pigs. In previous work, we proposed the body weight deviation from the …
The role of the Src Homology-2 domain containing protein B (SHB) in β cells
M Welsh, M Jamalpour, G Zang… - Journal of Molecular …, 2016 - jme.bioscientifica.com
This review will describe the SH2-domain signaling protein Src Homology-2 domain
containing protein B (SHB) and its role in various physiological processes relating in …
containing protein B (SHB) and its role in various physiological processes relating in …
Mouse Breast Carcinoma Monocytic/Macrophagic Myeloid-Derived Suppressor Cell Infiltration as a Consequence of Endothelial Dysfunction in Shb-Deficient …
Q He, M Jamalpour, E Bergquist, RL Anderson… - International Journal of …, 2021 - mdpi.com
Metastasis reflects both the inherent properties of tumor cells and the response of the stroma
to the presence of the tumor. Vascular barrier properties, either due to endothelial cell (EC) …
to the presence of the tumor. Vascular barrier properties, either due to endothelial cell (EC) …
Vascular dysfunction and increased metastasis of B16F10 melanomas in Shb deficient mice as compared with their wild type counterparts
G Zang, K Gustafsson, M Jamalpour, JW Hong… - BMC cancer, 2015 - Springer
Background Shb is a signaling protein downstream of vascular endothelial growth factor
receptor-2 and Shb deficiency has been found to restrict tumor angiogenesis. The present …
receptor-2 and Shb deficiency has been found to restrict tumor angiogenesis. The present …
The Src homology-2 protein Shb modulates focal adhesion kinase signaling in a BCR-ABL myeloproliferative disorder causing accelerated progression of disease
K Gustafsson, M Jamalpour, C Trinh… - Journal of hematology & …, 2014 - Springer
Abstract Background The Src homology-2 domain protein B (Shb) is an adapter protein
operating downstream of several tyrosine kinase receptors and consequently Shb regulates …
operating downstream of several tyrosine kinase receptors and consequently Shb regulates …
Aberrant association between vascular endothelial growth factor receptor-2 and VE-cadherin in response to vascular endothelial growth factor-a in Shb-deficient lung …
G Zang, G Christoffersson, G Tian, M Harun-Or-Rashid… - Cellular signalling, 2013 - Elsevier
Vascular permeability is a hallmark response to the main angiogenic factor VEGF-A and we
have previously described a reduction of this response in Shb knockout mice. To …
have previously described a reduction of this response in Shb knockout mice. To …
The Cdh5-CreERT2 transgene causes conditional Shb gene deletion in hematopoietic cells with consequences for immune cell responses to tumors
The tamoxifen-responsive conditional Cdh5-CreERT2 is commonly used for endothelial cell
specific conditional deletion of loxP-flanked gene sequences. To address the role of …
specific conditional deletion of loxP-flanked gene sequences. To address the role of …
[HTML][HTML] Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant …
B Åkerblom, G Zang, ZW Zhuang, G Calounova… - Molecular …, 2012 - Elsevier
The Shb adapter protein is a signaling intermediate that operates downstream of vascular
endothelial growth factor receptor-2 (VEGFR-2) in endothelial cells. The Shb knockout …
endothelial growth factor receptor-2 (VEGFR-2) in endothelial cells. The Shb knockout …
The Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activity
K Gustafsson, G Heffner, PL Wenzel, M Curran… - Experimental cell …, 2013 - Elsevier
The widely expressed adaptor protein Shb has previously been reported to contribute to T
cell function due to its association with the T cell receptor and furthermore, several of Shb's …
cell function due to its association with the T cell receptor and furthermore, several of Shb's …