Inflammation is a central mechanism for dealing with insults to tissue, either from pathogenic
invaders or by other damage-inducing means, such that the threat is removed, the tissue is …

A fine-tuned activation and deactivation of proteases and their inhibitors are involved in the
execution of the inflammatory response. The zymogen/proenzyme plasminogen is converted …

Abstract Background and Aims Despite the presence of neutrophil extracellular traps [NETs]
in inflamed colon having been confirmed, the role of NETs, especially the circulating NETs …

Tranexamic acid (TXA) is a popular antifibrinolytic drug widely used in hemorrhagic trauma
patients and cardiovascular, orthopedic, and gynecological surgical patients. TXA binds …

Crohn's disease (CD) is an inflammatory bowel disease (IBD) with repeated remissions and
relapses. As the disease progresses, fibrosis and narrowing of the intestine occur, leading to …

Owing to its immense surface area, the mucosal surface of the gastrointestinal (GI) tract is
continually subject to numerous endogenous and exogenous antigens capable of inducing …

Tissue regeneration during wound healing or cancer growth and progression depends on
the establishment of a cellular microenvironment. Mesenchymal stem cells (MSC) are part of …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), through its ability to
induce cytokine release syndrome, can set up a generalized inflammatory response …

The intestinal tract is a complex ecosystem where numerous cell types of epithelial, immune,
neuronal, and endothelial origin coexist in an intertwined, highly organized manner. The …

Adhesive small bowel obstruction remains a common problem for surgeons. After surgery,
platelet aggregation contributes to coagulation cascade and fibrin clot formation. With …