Global prevalence of mutation in the mgrB gene among clinical isolates of colistin-resistant Klebsiella pneumoniae: a systematic review and meta-analysis

A Khoshbayan, N Narimisa, Z Elahi… - Frontiers in …, 2024 - frontiersin.org
Background Colistin is used as a last resort for managing infections caused by multidrug-
resistant bacteria. However, the high emergence of colistin-resistant strains has restricted …

From farm to fork: Persistence of clinically relevant multidrug-resistant and copper-tolerant klebsiella pneumoniae long after colistin withdrawal in poultry production

J Mourão, M Ribeiro-Almeida, C Novais… - Microbiology …, 2023 - Am Soc Microbiol
Concerns about colistin-resistant bacteria in animal food-environmental-human ecosystems
prompted the poultry sector to implement colistin restrictions and explore alternative trace …

Genetic diversity of polymyxin-resistance mechanisms in clinical isolates of carbapenem-resistant Klebsiella pneumoniae: a multicenter study in China

Z Li, X Liu, Z Lei, C Li, F Zhang, Y Wu… - Microbiology …, 2023 - Am Soc Microbiol
Polymyxin has been the last resort to treat multidrug-resistant Klebsiella pneumonia.
However, recent studies have revealed that polymyxin-resistant carbapenem-resistant …

Genomic insights into the expansion of carbapenem-resistant Klebsiella pneumoniae within Portuguese hospitals

NA Faria, T Touret, AS Simões, C Palos, S Bispo… - Journal of Hospital …, 2024 - Elsevier
Carbapenem-resistant Klebsiella pneumoniae (CR-KP) are a public health concern, causing
infections with a high mortality rate, limited therapeutic options and challenging infection …

Mobile Colistin-Resistant Genes mcr-1, mcr-2, and mcr-3 Identified in Diarrheal Pathogens among Infants, Children, and Adults in Bangladesh: Implications for the …

S Sarker, RM Neeloy, MB Habib, UL Urmi, MA Asad… - Antibiotics, 2024 - mdpi.com
Colistin is a last-resort antimicrobial for treating multidrug-resistant Gram-negative bacteria.
Phenotypic colistin resistance is highly associated with plasmid-mediated mobile colistin …

In-depth characterization of multidrug-resistant NDM-1 and KPC-3 co-producing Klebsiella pneumoniae bloodstream isolates from Italian hospital patients

B Posteraro, F De Maio, Y Motro… - Microbiology …, 2024 - Am Soc Microbiol
Bloodstream infection (BSI) caused by carbapenem-resistant Klebsiella pneumoniae (KP)
poses significant challenges, particularly when the infecting isolate carries multiple …

Impact of PmrB mutations on clinical Klebsiella pneumoniae with variable colistin‐susceptibilities: Structural insights and potent therapeutic solutions

S Basu, B Veeraraghavan… - Chemical Biology & Drug …, 2024 - Wiley Online Library
Carbapenem‐resistant Klebsiella pneumoniae (CRKP) infections continue to impose high
morbidity threats to hospitalized patients worldwide, limiting therapeutic options to last …