[HTML][HTML] Role of hepatocyte nuclear factor 4-alpha in gastrointestinal and liver diseases
MM Yeh, DE Bosch, SS Daoud - World journal of gastroenterology, 2019 - ncbi.nlm.nih.gov
Hepatocyte nuclear factor 4-alpha (HNF4α) is a highly conserved member of nuclear
receptor superfamily of ligand-dependent transcription factors that is expressed in liver and …
receptor superfamily of ligand-dependent transcription factors that is expressed in liver and …
[PDF][PDF] Human milk lipids induce important metabolic and epigenetic changes in Neonates
K Donda, A Maheshwari - Clinics in perinatology, 2022 - Elsevier
Lipids are a major source of energy during the fetal/neonatal period. Most are received from
the mother, either transplacentally during the intrauterine period or via maternal milk after …
the mother, either transplacentally during the intrauterine period or via maternal milk after …
Elevated methylation of the vault RNA2-1 promoter in maternal blood is associated with preterm birth
YA You, EJ Kwon, HS Hwang, SJ Choi, SK Choi… - BMC genomics, 2021 - Springer
Background Preterm birth, defined as parturition before 37 completed weeks of gestation, is
associated with an increased risk of neonatal complications and death, as well as poor …
associated with an increased risk of neonatal complications and death, as well as poor …
Identification of TAF1, HNF4A, and CALM2 as potential therapeutic target genes for liver fibrosis
D Ji, GF Chen, JC Wang, LH Cao, F Lu… - Journal of Cellular …, 2019 - Wiley Online Library
The molecular mechanism of liver fibrosis caused by hepatitis C virus (HCV) is not clear. The
aim of this study is to understand the molecular mechanism of liver fibrosis induced by HCV …
aim of this study is to understand the molecular mechanism of liver fibrosis induced by HCV …
Prenatal bisphenol A exposure, DNA methylation, and low birth weight: a pilot study in Taiwan
Prenatal exposure to bisphenol A (BPA) may increase the risk of abnormal birth outcomes,
and DNA methylation might mediate these adverse effects. This study aimed to investigate …
and DNA methylation might mediate these adverse effects. This study aimed to investigate …
The obesogenic environment: Epigenetic modifications in placental melanocortin 4 receptor gene connected to gestational diabetes and smoking
M Franzago, A Porreca, M D'Ardes, M Di Nicola… - Frontiers in …, 2022 - frontiersin.org
Background Maternal metabolic insults as well as Gestational Diabetes Mellitus (GDM)
influence the fetal health and may affect 'offspring's susceptibility to chronic diseases via …
influence the fetal health and may affect 'offspring's susceptibility to chronic diseases via …
Methylation changes and pathways affected in preterm birth: a role for SLC6A3 in neurodevelopment
A Arpon, FI Milagro, A Laja, V Segura… - …, 2018 - Taylor & Francis
Aim: To analyze whether preterm newborns show differences in methylation patterns in
comparison to full-term newborns in white blood cells. Patients & methods …
comparison to full-term newborns in white blood cells. Patients & methods …
Association between the DNA methylations of POMC, MC4R, and HNF4A and metabolic profiles in the blood of children aged 7–9 years
EJ Kwon, YA You, B Park, EH Ha, HS Kim, H Park… - BMC pediatrics, 2018 - Springer
Abstract Background Proopiomelanocortin (POMC), melanocortin 4 receptor (MC4R), and
hepatocyte nuclear factor 4 alpha (HNF4A) are closely associated with weight gain and …
hepatocyte nuclear factor 4 alpha (HNF4A) are closely associated with weight gain and …
MC4R and HNF4α promoter methylation at birth contribute to triglyceride levels in childhood: a prospective cohort study
Although the changes in DNA methylation are assumed to be due to the association
between adverse intrauterine conditions and adult metabolic health, evidence from human …
between adverse intrauterine conditions and adult metabolic health, evidence from human …
Cord blood buffy coat DNA methylation is comparable to whole cord blood methylation
Cord blood DNA methylation is associated with numerous health outcomes and
environmental exposures. Whole cord blood DNA reflects all nucleated blood cell types …
environmental exposures. Whole cord blood DNA reflects all nucleated blood cell types …