Coumarins, a group of naturally occurring compounds, have been reported to demonstrate
anticancer potential. These substances, distinguished by their combined benzene and α …

Dengue virus enters the cell by receptor-mediated endocytosis followed by a viral envelope
(DENVE) protein-mediated membrane fusion. A small detergent molecule n-octyl-β-D …

Mitogen-activated protein kinases (MAPKs), also known as extracellular signal regulated
kinases (ERKs), are found in numerous signal transduction pathways and are triggered by …

One of the most common causes of mortality in COVID-19 patients is cytokine release
syndrome (CRS). Though several cytokines are involved in CRS, the role of Interleukin 6 is …

Background: Targeted therapies, specifically ErbB family tyrosine kinase inhibitors, have
demonstrated potential for improving outcomes in patients with ErbB2-positive breast …

The repurposing of FDA-approved Bruton's tyrosine kinase (BTK) inhibitors as therapeutic
agents for solid tumors may offer renewed hope for chemotherapy-resistant cancer patients …

Most of the effective anticancer drugs available in the market suffer from adverse effects due
to their lack of target specificity. Therefore, so many delivery systems have been explored to …

Background Selective estrogen receptor modulators (SERMs) block the effects of estrogen
on breast cancer cells by sitting in the estrogen receptors. If a SERM is in the estrogen …

It is observed that cytokine release syndrome (CRS) is one of the major causes for the death
of several COVID-19 patients. Though several cytokines are involved in CRS, Interleukin-6 …

Selective estrogen receptor modulators (SERMs) bind to estrogen receptors and prevent
estrogen from acting on breast cancer cells. A SERM prevents estrogen from attaching to the …