In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …

Emerging strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the
causative agent of the coronavirus disease 2019 (COVID-19) pandemic, that show …

Infection-related diabetes can arise as a result of virus-associated β-cell destruction. Clinical
data suggest that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is one of the deadliest pandemics in history. SARS …

Syncytia are formed when individual cells fuse. SARS-CoV-2 induces syncytia when the
viral spike (S) protein on the surface of an infected cell interacts with receptors on …

Virus entry, consisting of attachment to and penetration into the host target cell, is the first
step of the virus life cycle and is a critical 'do or die'event that governs virus emergence in …

Interferon-induced transmembrane proteins (IFITMs) are broad spectrum antiviral factors that
inhibit the entry of a wide range of clinically important pathogens including influenza A virus …

Type I interferons (IFN-I) are critical mediators of innate control of viral infections but also
drive the recruitment of inflammatory cells to sites of infection, a key feature of severe …

Abstract As coronavirus disease 2019 (COVID-19) and aging are both accompanied by
cognitive decline, we hypothesized that COVID-19 might lead to molecular signatures …

The nasal epithelium is a plausible entry point for SARS-CoV-2, a site of pathogenesis and
transmission, and may initiate the host response to SARS-CoV-2. Antiviral interferon (IFN) …