Metabolomics in cancer research and emerging applications in clinical oncology
Cancer has myriad effects on metabolism that include both rewiring of intracellular
metabolism to enable cancer cells to proliferate inappropriately and adapt to the tumor …
metabolism to enable cancer cells to proliferate inappropriately and adapt to the tumor …
Early screening and diagnosis strategies of pancreatic cancer: a comprehensive review
J Yang, R Xu, C Wang, J Qiu, B Ren… - Cancer …, 2021 - Wiley Online Library
Pancreatic cancer is a highly malignant digestive system tumor with a poor prognosis. Most
pancreatic cancer patients are diagnosed at an advanced stage or even metastasis due to …
pancreatic cancer patients are diagnosed at an advanced stage or even metastasis due to …
[HTML][HTML] Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes
A McGuigan, P Kelly, RC Turkington… - World journal of …, 2018 - ncbi.nlm.nih.gov
This review aims to outline the most up-to-date knowledge of pancreatic adenocarcinoma
risk, diagnostics, treatment and outcomes, while identifying gaps that aim to stimulate further …
risk, diagnostics, treatment and outcomes, while identifying gaps that aim to stimulate further …
Applications of multi‐omics analysis in human diseases
Multi‐omics usually refers to the crossover application of multiple high‐throughput screening
technologies represented by genomics, transcriptomics, single‐cell transcriptomics …
technologies represented by genomics, transcriptomics, single‐cell transcriptomics …
Integrated analysis of the faecal metagenome and serum metabolome reveals the role of gut microbiome-associated metabolites in the detection of colorectal cancer …
F Chen, X Dai, CC Zhou, K Li, Y Zhang, XY Lou… - Gut, 2022 - gut.bmj.com
Objective To profile gut microbiome-associated metabolites in serum and investigate
whether these metabolites could distinguish individuals with colorectal cancer (CRC) or …
whether these metabolites could distinguish individuals with colorectal cancer (CRC) or …
Cancer biomarkers and their biosensors: A comprehensive review
The article starts with a brief history of discovery of cancer biomarkers followed by statistical
data on published cancer biomarkers detection strategies in the last decade to demonstrate …
data on published cancer biomarkers detection strategies in the last decade to demonstrate …
To metabolomics and beyond: a technological portfolio to investigate cancer metabolism
F Danzi, R Pacchiana, A Mafficini, MT Scupoli… - … and Targeted Therapy, 2023 - nature.com
Tumour cells have exquisite flexibility in reprogramming their metabolism in order to support
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …
Recent advances in LC‐MS‐based metabolomics for clinical biomarker discovery
The employment of liquid chromatography‐mass spectrometry (LC‐MS) untargeted and
targeted metabolomics has led to the discovery of novel biomarkers and improved the …
targeted metabolomics has led to the discovery of novel biomarkers and improved the …
FeOOH@ metal–organic framework core–satellite nanocomposites for the serum metabolic fingerprinting of gynecological cancers
C Pei, C Liu, Y Wang, D Cheng, R Li, W Shu… - Angewandte …, 2020 - Wiley Online Library
High‐throughput metabolic analysis is of significance in diagnostics, while tedious sample
pretreatment has largely hindered its clinic application. Herein, we designed FeOOH@ ZIF …
pretreatment has largely hindered its clinic application. Herein, we designed FeOOH@ ZIF …
Chronic pancreatitis
Chronic pancreatitis is a multifactorial, fibroinflammatory syndrome in which repetitive
episodes of pancreatic inflammation lead to extensive fibrotic tissue replacement, resulting …
episodes of pancreatic inflammation lead to extensive fibrotic tissue replacement, resulting …