Nanomaterials for theranostics: recent advances and future challenges
In 2004, the US Food and Drug Administration (FDA) released an important report entitled
“Innovation/Stagnation: Challenge and Opportunity on the Critical Path to New Medical …
“Innovation/Stagnation: Challenge and Opportunity on the Critical Path to New Medical …
[HTML][HTML] Integrative multi-omics approaches in cancer research: from biological networks to clinical subtypes
YJ Heo, C Hwa, GH Lee, JM Park, JY An - Molecules and cells, 2021 - Elsevier
Multi-omics approaches are novel frameworks that integrate multiple omics datasets
generated from the same patients to better understand the molecular and clinical features of …
generated from the same patients to better understand the molecular and clinical features of …
Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8+ T cell exhaustion
DH Peng, BL Rodriguez, L Diao, L Chen… - Nature …, 2020 - nature.com
Tumor extracellular matrix has been associated with drug resistance and immune
suppression. Here, proteomic and RNA profiling reveal increased collagen levels in lung …
suppression. Here, proteomic and RNA profiling reveal increased collagen levels in lung …
Comprehensive molecular characterization of muscle-invasive bladder cancer
We report a comprehensive analysis of 412 muscle-invasive bladder cancers characterized
by multiple TCGA analytical platforms. Fifty-eight genes were significantly mutated, and the …
by multiple TCGA analytical platforms. Fifty-eight genes were significantly mutated, and the …
Integrated genomic characterization of pancreatic ductal adenocarcinoma
We performed integrated genomic, transcriptomic, and proteomic profiling of 150 pancreatic
ductal adenocarcinoma (PDAC) specimens, including samples with characteristic low …
ductal adenocarcinoma (PDAC) specimens, including samples with characteristic low …
Comprehensive and integrative genomic characterization of hepatocellular carcinoma
A Ally, M Balasundaram, R Carlsen, E Chuah, A Clarke… - Cell, 2017 - cell.com
Liver cancer has the second highest worldwide cancer mortality rate and has limited
therapeutic options. We analyzed 363 hepatocellular carcinoma (HCC) cases by whole …
therapeutic options. We analyzed 363 hepatocellular carcinoma (HCC) cases by whole …
Comprehensive and integrated genomic characterization of adult soft tissue sarcomas
Sarcomas are a broad family of mesenchymal malignancies exhibiting remarkable histologic
diversity. We describe the multi-platform molecular landscape of 206 adult soft tissue …
diversity. We describe the multi-platform molecular landscape of 206 adult soft tissue …
Integrated genomic characterization of papillary thyroid carcinoma
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Here, we
describe the genomic landscape of 496 PTCs. We observed a low frequency of somatic …
describe the genomic landscape of 496 PTCs. We observed a low frequency of somatic …
The integrated genomic landscape of thymic epithelial tumors
Thymic epithelial tumors (TETs) are one of the rarest adult malignancies. Among TETs,
thymoma is the most predominant, characterized by a unique association with autoimmune …
thymoma is the most predominant, characterized by a unique association with autoimmune …
[HTML][HTML] Genomic, pathway network, and immunologic features distinguishing squamous carcinomas
JD Campbell, C Yau, R Bowlby, Y Liu, K Brennan… - Cell reports, 2018 - cell.com
Summary This integrated, multiplatform PanCancer Atlas study co-mapped and identified
distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites …
distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites …