RNA interference: biology, mechanism, and applications

N Agrawal, PVN Dasaradhi, A Mohmmed… - Microbiology and …, 2003 - Am Soc Microbiol
Double-stranded RNA-mediated interference (RNAi) is a simple and rapid method of
silencing gene expression in a range of organisms. The silencing of a gene is a …

Fast forward genetics based on virus-induced gene silencing

DC Baulcombe - Current opinion in plant biology, 1999 - Elsevier
Gene expression in plants can be suppressed in a sequencespecific manner by infection
with virus vectors carrying fragments of host genes. Recent developments have revealed …

Construct design for efficient, effective and high‐throughput gene silencing in plants

SV Wesley, CA Helliwell, NA Smith, MB Wang… - The Plant …, 2001 - Wiley Online Library
Post‐transcriptional silencing of plant genes using anti‐sense or co‐suppression constructs
usually results in only a modest proportion of silenced individuals. Recent work has …

[HTML][HTML] Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance

P Mourrain, C Béclin, T Elmayan, F Feuerbach… - Cell, 2000 - cell.com
Posttranscriptional gene silencing (PTGS) in plants results from the degradation of mRNAs
and shows phenomenological similarities with quelling in fungi and RNAi in animals. Here …

[HTML][HTML] An RNA-dependent RNA polymerase gene in Arabidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus

T Dalmay, A Hamilton, S Rudd, S Angell… - Cell, 2000 - cell.com
Posttranscriptional gene silencing is a defense mechanism in plants that is similar to
quelling in fungi and RNA interference in animals. Here, we describe four genetic loci that …

[图书][B] Natural products from plants

LJ Cseke, A Kirakosyan, PB Kaufman, S Warber… - 2016 - api.taylorfrancis.com
2008 NOMINEE The Council on Botanical and Horticultural Libraries Annual Award for a
Significant Work in Botanical or Horticultural Literature From medicinal, industrial, and …

RNA-triggered gene silencing

A Fire - Trends in Genetics, 1999 - cell.com
Double-stranded RNA (dsRNA) has recently been shown to trigger sequence-specific gene
silencing in a wide variety of organisms, including nematodes, plants, trypanosomes, fruit …

High-stearic and high-oleic cottonseed oils produced by hairpin RNA-mediated post-transcriptional gene silencing

Q Liu, SP Singh, AG Green - Plant physiology, 2002 - academic.oup.com
We have genetically modified the fatty acid composition of cottonseed oil using the recently
developed technique of hairpin RNA-mediated gene silencing to down-regulate the seed …

AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals

M Fagard, S Boutet, JB Morel… - Proceedings of the …, 2000 - National Acad Sciences
Introduction of transgene DNA may lead to specific degradation of RNAs that are
homologous to the transgene transcribed sequence through phenomena named post …

RNA interference and small interfering RNAs

T Tuschl - Chembiochem, 2001 - Wiley Online Library
It has long been thought that sequence-specific PTGS required a nucleic acid polymer to
guide mRNA cleavage.[35] The presence of an antisense RNA species complementary to …