An efficient photochemical radical sulfonyl cyclization of designed dienes to medium-sized
benzo [b] azocines and benzo [b] azonines was developed. This chemoselective method …

The construction of N-heterocyclic eight-membered rings with good regio-, stereo-, and
enantioselective control remains a formidable challenge in asymmetric catalysis. Herein, we …

The development of protocols for constructing chiral medium-sized heterocycles with high
efficiency and excellent stereocontrol is of great interest owing to their ubiquitous occurrence …

The preparation of medium-sized benzo [b] azocines has always been challenging because
of inherently unfavorable enthalpy and entropy factors. This report presents a novel …

Oxo-bridged dibenzoazocines are furnished within a single synthetic step at room
temperature via ruthenium-catalyzed [4+ 3]-cycloannulation of aza-ortho-quinone methides …

An enantioselective Michael addition–four‐atom ring expansion cascade reaction involving
cyclobutanones activated by a N‐aryl secondary amide group and ortho‐amino …

Constructing eight-membered rings, especially in an enantioselective manner, is a
challenging task due to unfavorable enthalpic and entropic barriers of the transition states …

Medium-sized nitrogen heterocycles, including eight-membered lactams, are important in
synthetic and pharmaceutical chemistry because of their presence in a variety of natural …

We report a highly efficient and diastereoselective gold and palladium sequential relay
catalysis system for the synthesis of furan-fused eight-membered heterocycles. Employing a …

Based on previous finding showing 2, 3, 6, 11-tetrahydro-1H-azocino [4, 5-b] indole as
suitable scaffold of novel inhibitors of acetylcholinesterase (AChE), a main target of drugs for …