The role of the interleukin (IL)-6/IL-6 receptor axis in cancer

MY Taher, DM Davies, J Maher - Biochemical Society …, 2018 - portlandpress.com
Interleukin-6 (IL-6) is a pleiotropic cytokine that activates a classic signalling pathway upon
binding to its membrane-bound receptor (IL-6R). Alternatively, IL-6 may 'trans-signal'in a …

Overview on molecular biomarkers for laryngeal cancer: looking for new answers to an old problem

M Falco, C Tammaro, T Takeuchi, AM Cossu… - Cancers, 2022 - mdpi.com
Simple Summary Laryngeal cancer represents one of the most common head and neck
cancers worldwide. It can arise in different larynx subsites, each associated with specific …

Increased levels of circulating interleukin 6, interleukin 8, C-reactive protein, and risk of lung cancer

SR Pine, LE Mechanic, L Enewold… - Journal of the …, 2011 - academic.oup.com
Background Previous studies that were based primarily on small numbers of patients
suggested that certain circulating proinflammatory cytokines may be associated with lung …

[PDF][PDF] RETRACTED ARTICLE: IL-6/STAT3 Signaling Contributes to Sorafenib Resistance in Hepatocellular Carcinoma Through Targeting Cancer Stem Cells

Y Li, G Chen, Z Han, H Cheng, L Qiao… - OncoTargets and …, 2020 - Taylor & Francis
Li Y, Chen G, Han Z, Cheng H, Qiao L, Li Y. Onco Targets Ther. 2020; 13: 9721–9730. The
Editor and Publisher of OncoTargets and Therapy wish to retract the published article …

Increased expression of interleukin-6 predicts poor response to chemoradiotherapy and unfavorable prognosis in oral squamous cell carcinoma

T Jinno, S Kawano, Y Maruse… - Oncology …, 2015 - spandidos-publications.com
Recent studies have revealed that cancer cells are exacerbated by chronic inflammation.
The present study examined the immunohistochemical expression for interleukin-6 (IL-6), a …

Transforming Spirulina maxima Biomass into Ultrathin Bioactive Coatings Using an Atmospheric Plasma Jet: A New Approach to Healing of Infected Wounds

T Pham, TT Nguyen, NH Nguyen, A Hayles, W Li… - Small, 2023 - Wiley Online Library
The challenge of wound healing, particularly in patients with comorbidities such as diabetes,
is intensified by wound infection and the accelerating problem of bacterial resistance to …

[HTML][HTML] Association between interleukin-6 and head and neck squamous cell carcinoma: A systematic review

U Uz, G Eskiizmir - Clinical and experimental …, 2021 - synapse.koreamed.org
Abstract Interleukin-6 (IL-6) is a proinflammatory cytokine which plays an important role in
several regulatory mechanisms of cancer. Moreover, experimental and clinical studies have …

Interleukin-6 role in head and neck squamous cell carcinoma progression

MM Choudhary, TJ France, TN Teknos… - World journal of …, 2016 - mednexus.org
Interleukin-6 (IL-6) is a pleiotropic cytokine which plays an important role in a number of
cellular processes including proliferation, survival, differentiation, migration and invasion. IL …

[HTML][HTML] Increased interleukin-6 expression is associated with poor prognosis and acquired cisplatin resistance in head and neck squamous cell carcinoma

J Gao, S Zhao, TS Halstensen - Oncology reports, 2016 - spandidos-publications.com
Increased expression of interleukin 6 (IL-6) is associated with poor prognosis and
chemoresistance in many different carcinomas, but its role in head and neck squamous cell …

C-reactive protein, interleukin 6 and lung cancer risk: a meta-analysis

B Zhou, J Liu, ZM Wang, T Xi - 2012 - journals.plos.org
Purpose Epidemiologic findings are inconsistent concerning the associations between C-
reactive protein (CRP), interleukin 6 (IL-6) and lung cancer risk. We conducted a meta …