[HTML][HTML] SERS sensing for cancer biomarker: Approaches and directions

L Vázquez-Iglesias, GMS Casagrande, D García-Lojo… - Bioactive Materials, 2024 - Elsevier
These days, cancer is thought to be more than just one illness, with several complex
subtypes that require different screening approaches. These subtypes can be distinguished …

Advances of surface-enhanced Raman spectroscopy in exosomal biomarkers analysis

HS Tan, T Wang, HN Sun, A Liu, SS Li - TrAC Trends in Analytical …, 2023 - Elsevier
Cancer derived exosomal biomarkers (eg proteins, RNAs) could reflect important
information about the cancer microenvironment. For ultrasensitive analysis of exosomal …

In situ synthesis and dynamic simulation of molecularly imprinted polymeric nanoparticles on a micro-reactor system

Ö Erdem, I Eş, Y Saylan, M Atabay, MA Gungen… - Nature …, 2023 - nature.com
Current practices in synthesizing molecularly imprinted polymers face challenges—lengthy
process, low-productivity, the need for expensive and sophisticated equipment, and they …

Standardization approaches for extracellular vesicle loading with oligonucleotides and biologics

J Roerig, M Schulz‐Siegmund - Small, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are widely recognized for their potential as drug delivery
systems. EVs are membranous nanoparticles shed from cells. Among their natural features …

Communicating Supraparticles to Enable Perceptual, Information‐Providing Matter

J Reichstein, S Müssig, S Wintzheimer… - Advanced …, 2023 - Wiley Online Library
Materials are the fundament of the physical world, whereas information and its exchange are
the centerpieces of the digital world. Their fruitful synergy offers countless opportunities for …

Advanced Nanoencapsulation-Enabled Ultrasensitive Analysis: Unraveling Tumor Extracellular Vesicle Subpopulations for Differential Diagnosis of Hepatocellular …

X Li, Y Liu, Y Fan, G Tian, B Shen, S Zhang, X Fu… - ACS …, 2024 - ACS Publications
Tumor-derived extracellular vesicles (tEVs) hold immense promise as potential biomarkers
for the precise diagnosis of hepatocellular carcinoma (HCC). However, their clinical …

[HTML][HTML] Cancer diagnosis using label-free SERS-based exosome analysis

Y Liu, M Li, H Liu, C Kang, C Wang - Theranostics, 2024 - ncbi.nlm.nih.gov
Exosomes, carrying distinctive biomolecules reflective of their parent cell's status and origin,
show promise as liquid biopsy biomarkers for cancer diagnosis. However, their clinical …

Application of artificial intelligence (AI)-enhanced biochemical sensing in molecular diagnosis and imaging analysis: Advancing and challenges

H Li, H Xu, Y Li, X Li - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Biochemical sensing plays a vital role in the research of life and natural science. However,
with the increase of environmental complexity and amount of sample, traditional sensors …

[HTML][HTML] Engineered extracellular vesicles (EVs): Promising diagnostic/therapeutic tools for pediatric high-grade glioma

Y Lyu, Y Guo, CM Okeoma, Z Yan, N Hu, Z Li… - Biomedicine & …, 2023 - Elsevier
Diffuse intrinsic pontine glioma (DIPG) is a highly malignant brain tumor that mainly occurs
in children with extremely low overall survival. Traditional therapeutic strategies, such as …

Optical microscopic and spectroscopic detection of exosomes

J Wei, T Qi, C Hao, S Zong, Z Wang, Y Cui - TrAC Trends in Analytical …, 2023 - Elsevier
Exosomes are extracellular vesicles with a diameter of 30–150 nm, they can reflect the
biological information of their parent cells and participate in intercellular communication …