Alzheimer's disease and its treatment by different approaches: A review
Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mental ability
development and interrupts neurocognitive function. This neuropathological condition is …
development and interrupts neurocognitive function. This neuropathological condition is …
[HTML][HTML] Magnetic iron oxide nanoparticles for brain imaging and drug delivery
Central nervous system (CNS) disorders affect as many as 1.5 billion people globally. The
limited delivery of most imaging and therapeutic agents into the brain is a major challenge …
limited delivery of most imaging and therapeutic agents into the brain is a major challenge …
Cell-penetrating peptides in diagnosis and treatment of human diseases: from preclinical research to clinical application
J Xie, Y Bi, H Zhang, S Dong, L Teng, RJ Lee… - Frontiers in …, 2020 - frontiersin.org
Cell-penetrating peptides (CPPs) are short peptides (fewer than 30 amino acids) that have
been predominantly used in basic and preclinical research during the last 30 years. Since …
been predominantly used in basic and preclinical research during the last 30 years. Since …
Solid lipid nanoparticles for hydrophilic drugs
Y Mirchandani, VB Patravale, S Brijesh - Journal of Controlled Release, 2021 - Elsevier
Hydrophilic drugs are proficient therapeutic agents however, delivery of these drugs is a
difficult task. Hence, developing an efficient drug delivery system may require a …
difficult task. Hence, developing an efficient drug delivery system may require a …
Chitosan on the surface of nanoparticles for enhanced drug delivery: A comprehensive review
The ability of chitosan (CTS) to promote mucoadhesion, trigger positive/negative surface
interactions, and open tight junctions has inspired researchers to coat lipid-based and …
interactions, and open tight junctions has inspired researchers to coat lipid-based and …
Recent advances in siRNA delivery mediated by lipid-based nanoparticles
S Yonezawa, H Koide, T Asai - Advanced drug delivery reviews, 2020 - Elsevier
Small interfering RNA (siRNA) has been expected to be a unique pharmaceutic for the
treatment of broad-spectrum intractable diseases. However, its unfavorable properties such …
treatment of broad-spectrum intractable diseases. However, its unfavorable properties such …
A review on advances of treatment modalities for Alzheimer's disease
Alzheimer's disease (AD) is a multifactorial neurodegenerative disease which is mainly
characterized by progressive impairment in cognition, emotion, language and memory in …
characterized by progressive impairment in cognition, emotion, language and memory in …
Nanotherapeutics for nose-to-brain drug delivery: an approach to bypass the blood brain barrier
D Lee, T Minko - Pharmaceutics, 2021 - mdpi.com
Treatment of neurodegenerative diseases or other central nervous system (CNS) disorders
has always been a significant challenge. The nature of the blood-brain barrier (BBB) limits …
has always been a significant challenge. The nature of the blood-brain barrier (BBB) limits …
[HTML][HTML] Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics
Central nervous system (CNS) disorders (eg, multiple sclerosis, Alzheimer's disease, etc.)
represent a growing public health issue, primarily due to the increased life expectancy and …
represent a growing public health issue, primarily due to the increased life expectancy and …
Nanoemulsions for “nose-to-brain” drug delivery
The blood–brain barrier (BBB) plays a fundamental role in protecting the brain from toxic
substances and therefore also controls and restricts the entry of therapeutic agents. The …
substances and therefore also controls and restricts the entry of therapeutic agents. The …