Beyond binding: antibody effector functions in infectious diseases

LL Lu, TJ Suscovich, SM Fortune, G Alter - Nature Reviews Immunology, 2018 - nature.com
Antibodies play an essential role in host defence against pathogens by recognizing
microorganisms or infected cells. Although preventing pathogen entry is one potential …

Intracellular pathogens: host immunity and microbial persistence strategies

A Thakur, H Mikkelsen… - Journal of immunology …, 2019 - Wiley Online Library
Infectious diseases caused by pathogens including viruses, bacteria, fungi, and parasites
are ranked as the second leading cause of death worldwide by the World Health …

The function of Fcγ receptors in dendritic cells and macrophages

M Guilliams, P Bruhns, Y Saeys, H Hammad… - Nature Reviews …, 2014 - nature.com
Dendritic cells (DCs) and macrophages use various receptors to recognize foreign antigens
and to receive feedback control from adaptive immune cells. Although it was long believed …

Potent antibacterial nanoparticles against biofilm and intracellular bacteria

H Mu, J Tang, Q Liu, C Sun, T Wang, J Duan - Scientific reports, 2016 - nature.com
The chronic infections related to biofilm and intracellular bacteria are always hard to be
cured because of their inherent resistance to both antimicrobial agents and host defenses …

The Mycobacterium tuberculosis capsule: a cell structure with key implications in pathogenesis

R Kalscheuer, A Palacios, I Anso, J Cifuente… - Biochemical …, 2019 - portlandpress.com
Bacterial capsules have evolved to be at the forefront of the cell envelope, making them an
essential element of bacterial biology. Efforts to understand the Mycobacterium tuberculosis …

B cells and antibodies in the defense against Mycobacterium tuberculosis infection

JM Achkar, J Chan, A Casadevall - Immunological reviews, 2015 - Wiley Online Library
Better understanding of the immunological components and their interactions necessary to
prevent or control Mycobacterium tuberculosis (Mtb) infection in humans is critical for …

The streptomycin mouse model for Salmonella diarrhea: functional analysis of the microbiota, the pathogen's virulence factors, and the host's mucosal immune …

P Kaiser, M Diard, B Stecher… - Immunological reviews, 2012 - Wiley Online Library
The mammalian intestine is colonized by a dense microbial community, the microbiota.
Homeostatic and symbiotic interactions facilitate the peaceful co‐existence between the …

B-cells and antibodies as contributors to effector immune responses in tuberculosis

WF Rijnink, THM Ottenhoff, SA Joosten - Frontiers in immunology, 2021 - frontiersin.org
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is still a major threat to
mankind, urgently requiring improved vaccination and therapeutic strategies to reduce TB …

Antibacterial effects of carbon dots in combination with other antimicrobial reagents

X Dong, MA Awak, N Tomlinson, Y Tang, YP Sun… - PloS one, 2017 - journals.plos.org
This study was designed to investigate the antimicrobial effects of CDots in combination with
other antimicrobial reagents, including H2O2, Na2CO3, and AcOH (acetic acid). CDots were …

Host immunomodulation strategies to combat pandemic-associated antimicrobial-resistant secondary bacterial infections

S Raghavan, K Kim - International Journal of Antimicrobial Agents, 2024 - Elsevier
The incidence of secondary bacterial infections has increased in recent decades owing to
various viral pandemics. These infections further increase the morbidity and mortality rates …