Assay devices designed for these applications offer improvements to existing methods or
provide fundamentally new strategies. Both mature methods and novel techniques have …

Abstract Characterization of the in vivo behavior of nanomaterials aims to optimize their
design, to determine their biological effects, and to validate their application. The …

Infections from parasitic nematodes (or roundworms) contribute to a significant disease
burden and productivity losses for humans and livestock. The limited number of …

Neuronal responses to sensory inputs can vary based on genotype, development,
experience, or stochastic factors. Existing neuronal recording techniques examine a single …

For more than four decades, the free-living nematode Caenorhabditis elegans has been
extensively used in anthelmintic research. Classic genetic screens and heterologous …

New microfluidic systems for whole organism analysis and experimentation are catalyzing
biological breakthroughs across many fields, from human health to fundamental biology …

Animal behaviors are commonly organized into long-lasting states that coordinately impact
the generation of diverse motor outputs such as feeding, locomotion, and grooming …

Plant-parasitic nematodes cause substantial damage to agricultural crops worldwide. Long-
term management of these pests requires novel strategies to reduce infection of host plants …

The forces generated by action potentials in muscle cells shuttle blood, food and waste
products throughout the luminal structures of the body. Although non-invasive …

The last half-century has provided all of the (few) drugs currently used to treat human
helminthiases. Concern regarding the long-term utility of these drugs, given how readily …