CSF and blood glial fibrillary acidic protein for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis

Y Zou, Y Wang, X Ma, D Mu, J Zhong, C Ma… - Ageing Research …, 2024 - Elsevier
Recently included in the 2024 new revised diagnostic criteria of Alzheimer's disease (AD),
glial fibrillary acidic protein (GFAP) has garnered significant attention. A systematic review …

Present and future of Blood-Based biomarkers of Alzheimer's Disease: Beyond the classics

MM Grigoli, LNC Pelegrini, R Whelan, MR Cominetti - Brain research, 2024 - Elsevier
The field of blood-based biomarkers for Alzheimer's disease (AD) has advanced at an
incredible pace, especially after the development of sensitive analytic platforms that can …

Proteomic Indicators of Health Predict Alzheimer's Disease Biomarker Levels and Dementia Risk

HE Dark, C Paterson, GN Daya, Z Peng… - Annals of …, 2024 - Wiley Online Library
Objective Few studies have comprehensively examined how health and disease risk
influence Alzheimer's disease (AD) biomarkers. The present study examined the association …

Longitudinal associations of serum biomarkers with early cognitive, amyloid and grey matter changes

S De Meyer, ER Blujdea, J Schaeverbeke, M Reinartz… - Brain, 2024 - academic.oup.com
Blood-based biomarkers have been extensively evaluated for their diagnostic potential in
Alzheimer's disease. However, their relative prognostic and monitoring capabilities for …

[HTML][HTML] Proteome-wide analysis identifies plasma immune regulators of amyloid-beta progression

MR Duggan, GT Gomez, CM Joynes, M Bilgel… - Brain, Behavior, and …, 2024 - Elsevier
While immune function is known to play a mechanistic role in Alzheimer's disease (AD),
whether immune proteins in peripheral circulation influence the rate of amyloid-β (Aβ) …

[HTML][HTML] Trajectories of CSF and plasma biomarkers across Alzheimer's disease continuum: disease staging by NF-L, p-tau181, and GFAP

AL Wojdała, G Bellomo, L Gaetani, A Toja, E Chipi… - Neurobiology of …, 2023 - Elsevier
CSF-to-plasma transition will open new avenues for molecular phenotyping of Alzheimer's
disease (AD). Here we evaluated a panel of AD biomarkers in matched CSF and plasma …

The impact of exercise on blood-based biomarkers of Alzheimer's disease in cognitively unimpaired older adults

KR Sewell, SR Rainey-Smith, S Pedrini, JJ Peiffer… - GeroScience, 2024 - Springer
Physical activity is a promising preventative strategy for Alzheimer's disease: it is associated
with lower dementia risk, better cognition, greater brain volume and lower brain beta …

Validating blood tests as a possible routine diagnostic assay of Alzheimer's disease

E Kodosaki, H Zetterberg… - Expert Review of …, 2023 - Taylor & Francis
Introduction In recent years, exciting developments in disease modifying treatments for
Alzheimer's disease (AD) have made accurate and timely diagnosis of this disease a priority …

Plasma p‐tau217, p‐tau181, and NfL as early indicators of dementia risk in a community cohort: The Shanghai Aging Study

Z Xiao, W Wu, X Ma, J Wu, X Liang… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION Blood biomarkers showed values for predicting future cognitive
impairment. Evidence from the community‐based cohort was limited only in high‐income …

Association of plasma biomarkers with cognition, cognitive decline, and daily function across and within neurodegenerative diseases: Results from the Ontario …

E Sanchez, T Wilkinson, G Coughlan… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION We investigated whether novel plasma biomarkers are associated with
cognition, cognitive decline, and functional independence in activities of daily living across …