The gastrointestinal tract plays a role in the development and treatment of metabolic
diseases. During a meal, the gut provides crucial information to the brain regarding …

Gamma-aminobutyric acid (Gaba) is a non-proteinogenic amino acid that is widely present
in microorganisms, plants, and vertebrates. So far, Gaba is well known as a main inhibitory …

Small, soluble metabolites not only are essential intermediates in intracellular biochemical
processes, but can also influence neighbouring cells when released into the extracellular …

The intestinal microbiota has been implicated in insulin resistance, although evidence
regarding causality in humans is scarce. We therefore studied the effect of lean donor …

Exercise is an effective strategy for diabetes management but is limited by the phenomenon
of exercise resistance (ie, the lack of or the adverse response to exercise on metabolic …

The central role of the intestinal microbiota in the progression and, equally, prevention of
metabolic dysfunction is becoming abundantly apparent. The symbiotic relationship …

Background The evidence for vitamin D and other agents that experimentally modulate T
regulatory cells (Tregs) for the treatment of patients with autoimmune or allergic diseases …

What is more interesting about brown adipose tissue (BAT) is its ability to provide
thermogenesis, protection against obesity by clearing triglycerides, releasing batokines, and …

In recent years, it has become clear that there is an extensive cross-talk between the
nervous and the immune system. Somewhat surprisingly, the immune cells themselves do …

In recent years, some new processes have been proposed to explain how alcohol may
influence behavior, psychological symptoms and alcohol seeking in alcohol-dependent …