Peptide drug development has made great progress in the last decade thanks to new
production, modification, and analytic technologies. Peptides have been produced and …

Natriuretic peptides, which are activated in heart failure, play an important cardioprotective
role. The most notable of the cardioprotective natriuretic peptides are atrial natriuretic …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted through October 2011 and includes selected …

Natriuretic peptides, brain (B-type) natriuretic peptide (BNP) and N-terminal prohormone of
brain natriuretic peptide (NT-proBNP) are globally and most often used for the diagnosis of …

Acute kidney injury (AKI) is a common and serious problem affecting millions and causing
death and disability for many. In 2012, Kidney Disease: Improving Global Outcomes …

After its discovery in the early 1980s, the natriuretic peptide (NP) system has been
extensively characterized and its potential influence in the development and progression of …

Background Nesiritide is approved in the United States for early relief of dyspnea in patients
with acute heart failure. Previous meta-analyses have raised questions regarding renal …

It is important that the medical profession play a significant role in critically evaluating the
use of diagnostic procedures and therapies as they are introduced and tested in the …

Late-breaking clinical trials presented at the 2005, 2006, and 2007 annual scientific
meetings of the ACCF, AHA, and European Society of Cardiology, as well as selected other …

Background Evidence-based medicine is valuable to the extent that the evidence base is
complete and unbiased. Selective publication of clinical trials—and the outcomes within …