The role of viral infections in the onset of autoimmune diseases
B Sundaresan, F Shirafkan, K Ripperger, K Rattay - Viruses, 2023 - mdpi.com
Autoimmune diseases (AIDs) are the consequence of a breach in immune tolerance,
leading to the inability to sufficiently differentiate between self and non-self. Immune …
leading to the inability to sufficiently differentiate between self and non-self. Immune …
Immune cell trafficking across the blood-brain barrier in the absence and presence of neuroinflammation
L Marchetti, B Engelhardt - Vascular Biology, 2020 - vb.bioscientifica.com
To maintain the homeostatic environment required for proper function of central nervous
system (CNS) neurons the endothelial cells of CNS microvessels tightly regulate the …
system (CNS) neurons the endothelial cells of CNS microvessels tightly regulate the …
Antigen recognition detains CD8+ T cells at the blood-brain barrier and contributes to its breakdown
S Aydin, J Pareja, VM Schallenberg, A Klopstein… - Nature …, 2023 - nature.com
Blood-brain barrier (BBB) breakdown and immune cell infiltration into the central nervous
system (CNS) are early hallmarks of multiple sclerosis (MS). High numbers of CD8+ T cells …
system (CNS) are early hallmarks of multiple sclerosis (MS). High numbers of CD8+ T cells …
Potential application of exosomes in vaccine development and delivery
MN Huda, M Nurunnabi - Pharmaceutical Research, 2022 - Springer
Exosomes are cell-derived components composed of proteins, lipid, genetic information,
cytokines, and growth factors. They play a vital role in immune modulation, cell-cell …
cytokines, and growth factors. They play a vital role in immune modulation, cell-cell …
Intercellular adhesion molecule 1: more than a leukocyte adhesion molecule
CD Haydinger, LM Ashander, ACR Tan, JR Smith - Biology, 2023 - mdpi.com
Simple Summary Intercellular adhesion molecule 1 (ICAM-1) is a protein produced by cells
in blood vessel walls, as well as many other cell types. It localizes to the surface of these …
in blood vessel walls, as well as many other cell types. It localizes to the surface of these …
ICAMs in immunity, intercellular adhesion and communication
C Guerra-Espinosa, M Jiménez-Fernández… - Cells, 2024 - mdpi.com
Interactions among leukocytes and leukocytes with immune-associated auxiliary cells
represent an essential feature of the immune response that requires the involvement of cell …
represent an essential feature of the immune response that requires the involvement of cell …
AIM2 deletion enhances blood‐brain barrier integrity in experimental ischemic stroke
S Xu, H Bian, S Shu, S Xia, Y Gu… - CNS Neuroscience …, 2021 - Wiley Online Library
Aims Ischemic stroke is a life‐threatening disease with limited therapeutic strategies. Blood‐
brain barrier (BBB) disruption is a critical pathological process that contributes to poor …
brain barrier (BBB) disruption is a critical pathological process that contributes to poor …
Oncostatin M triggers brain inflammation by compromising blood–brain barrier integrity
D Hermans, E Houben, P Baeten, H Slaets… - Acta …, 2022 - Springer
Oncostatin M (OSM) is an IL-6 family member which exerts neuroprotective and
remyelination-promoting effects after damage to the central nervous system (CNS) …
remyelination-promoting effects after damage to the central nervous system (CNS) …
Brain endothelial tricellular junctions as novel sites for T cell diapedesis across the blood–brain barrier
M Castro Dias, A Odriozola Quesada… - Journal of cell …, 2021 - journals.biologists.com
The migration of activated T cells across the blood–brain barrier (BBB) is a critical step in
central nervous system (CNS) immune surveillance and inflammation. Whereas T cell …
central nervous system (CNS) immune surveillance and inflammation. Whereas T cell …
HMGB1/PI3K/Akt/mTOR signaling participates in the pathological process of acute lung injury by regulating the maturation and function of dendritic cells
R Li, X Zou, H Huang, Y Yu, H Zhang, P Liu… - Frontiers in …, 2020 - frontiersin.org
Background: High-mobility group box 1 protein (HMGB1) was identified as a highly
conserved DNA binding nuclear protein, which participates in the processes of acute lung …
conserved DNA binding nuclear protein, which participates in the processes of acute lung …