Biomimetic cell culture, which involves creating a biomimetic microenvironment for cells in
vitro by engineering approaches, has aroused increasing interest given that it maintains the …

Abstract Organ‐on‐a‐chip, also known as “tissue chip,” is an advanced platform based on
microfluidic systems for constructing miniature organ models in vitro. They can replicate the …

Addressing large bone defects remains a significant challenge owing to the inherent
limitations in self‐healing capabilities, resulting in prolonged recovery and suboptimal …

Musculoskeletal (MSK) disorders significantly burden patients and society, resulting in high
healthcare costs and productivity loss. These disorders are the leading cause of physical …

Human organotypic bone models are an emerging technology that replicate bone
physiology and mechanobiology for comprehensive in vitro experimentation over prolonged …

Bone differentiation is crucial for skeletal development and maintenance. Its dysfunction can
cause various pathological conditions such as rickets, osteoporosis, osteogenesis …

Organoids are self-organized, three-dimensional structures derived from stem cells that can
mimic the structure and physiology of human organs. Patient-specific induced pluripotent …

Delayed fracture healing is the improper healing of fractures within a reasonable amount of
time and is estimated to impact a sixth of all fractures that occur annually in the United …

Biomimetic cell culture, which is committed to creating a biomimetic microenvironment for
cells in vitro by engineering approaches, has aroused increasing interest. In this review …