[HTML][HTML] 5-Fluorouracil (5-FU) resistance and the new strategy to enhance the sensitivity against cancer: Implication of DNA repair inhibition
Fluorouracil (5-FU) has been an important anti-cancer drug to date. With an increase in the
knowledge of its mechanism of action, various treatment modalities have been developed …
knowledge of its mechanism of action, various treatment modalities have been developed …
Ferroptosis-driven nanotherapeutics for cancer treatment
X Shan, S Li, B Sun, Q Chen, J Sun, Z He… - Journal of Controlled …, 2020 - Elsevier
The clinical efficacy of existing cancer therapies is still far from satisfactory. There is an
urgent need to integrate the emerging biomedical discovery and technological innovation …
urgent need to integrate the emerging biomedical discovery and technological innovation …
Nanoparticles in cancer diagnosis and treatment
The use of tailored medication delivery in cancer treatment has the potential to increase
efficacy while decreasing unfavourable side effects. For researchers looking to improve …
efficacy while decreasing unfavourable side effects. For researchers looking to improve …
[HTML][HTML] Molecular targets, therapeutic agents and multitasking nanoparticles to deal with cancer stem cells: A narrative review
There is increasing evidence that malignant tumors are initiated and maintained by a sub-
population of tumor cells that have similar biological properties to normal adult stem cells …
population of tumor cells that have similar biological properties to normal adult stem cells …
[HTML][HTML] Ferroptosis in colorectal cancer: Potential mechanisms and effective therapeutic targets
Y Wang, Z Zhang, W Sun, J Zhang, Q Xu, X Zhou… - Biomedicine & …, 2022 - Elsevier
Colorectal cancer (CRC) is a common malignant tumor characterized by unchecked division
and survival of abnormal cells in the colon or rectum with high morbidity and mortality …
and survival of abnormal cells in the colon or rectum with high morbidity and mortality …
Nanoparticles for targeted drug delivery to cancer stem cells: a review of recent advances
Cancer stem cells (CSCs) are a subpopulation of cells that can initiate, self-renew, and
sustain tumor growth. CSCs are responsible for tumor metastasis, recurrence, and drug …
sustain tumor growth. CSCs are responsible for tumor metastasis, recurrence, and drug …
Tumour microenvironment stress promotes the development of drug resistance
Multi-drug resistance (MDR) is a leading cause of cancer-related death, and it continues to
be a major barrier to cancer treatment. The tumour microenvironment (TME) has proven to …
be a major barrier to cancer treatment. The tumour microenvironment (TME) has proven to …
Nanotechnology-based diagnostics and therapeutics in acute lymphoblastic leukemia: a systematic review of preclinical studies
R Khademi, Z Mohammadi, R Khademi… - Nanoscale …, 2023 - pubs.rsc.org
Background: Leukemia is a malignant disease that threatens human health and life. Nano-
delivery systems improve drug solubility, bioavailability, and blood circulation time, and …
delivery systems improve drug solubility, bioavailability, and blood circulation time, and …
Recent progress on nanomedicine-induced ferroptosis for cancer therapy
The current treatment strategies for cancer therapy have posed many problems in achieving
high efficacy. Therefore, an urgent step is needed to develop innovative therapies that can …
high efficacy. Therefore, an urgent step is needed to develop innovative therapies that can …
Ferroptosis-inducing nanomedicine for cancer therapy
Y Wang, T Liu, X Li, H Sheng, X Ma… - Frontiers in Pharmacology, 2021 - frontiersin.org
Ferroptosis, a new iron-and reactive oxygen species–dependent form of regulated cell
death, has attracted much attention in the therapy of various types of tumors. With the …
death, has attracted much attention in the therapy of various types of tumors. With the …