Epigenetic mechanisms control gene activity and the development of an organism. The
epigenome includes DNA methylation, histone modifications, and RNA-mediated processes …

Multiple recent studies highlight that genetic variants can have strong impacts on a
significant proportion of the human DNA methylome. Methylation quantitative trait loci, or …

Although more studies are demonstrating that a father's environment can influence child
health and disease, the molecular mechanisms underlying non-genetic inheritance remain …

Once deemed heretical, emerging evidence now supports the notion that the inheritance of
acquired characteristics can occur through ancestral exposures or experiences and that …

Pivotal to projecting the fate of coral reefs is the capacity of reef-building corals to
acclimatize and adapt to climate change. Transgenerational plasticity may enable some …

Obesity is a heritable disorder, with children of obese fathers at higher risk of developing
obesity. Environmental factors epigenetically influence somatic tissues, but the contribution …

Using olfactory molecular specificity, we examined the inheritance of parental traumatic
exposure, a phenomenon that has been frequently observed, but not understood. We …

Research efforts during the past decades have provided intriguing evidence suggesting that
stressful experiences during pregnancy exert long-term consequences on the future mental …

Genome-wide DNA methylation reprogramming occurs in mouse primordial germ cells
(PGCs) and preimplantation embryos, but the precise dynamics and biological outcomes are …

BACKGROUND A defining feature of sexual reproduction is the transmission of genomic
information from both parents to the offspring. There is now compelling evidence that the …