The interaction of Rebeccamycin with calf thymus (ctDNA) in the absence and presence of
H1 was investigated by molecular dynamics, multi-spectroscopic, and cellular techniques …

Abstract β-resorcylic acid (BR) is a phytochemical which is widely used in the food industry
as a flavouring agent and preservative. It has also been found to exhibit antibacterial action …

The interaction between ofloxacin (Oflx) and calf thymus DNA (ct DNA) in the presence and
absence of histone H1 was investigated in Tris buffer (pH= 6.8) using UV–vis absorption and …

Combination therapy based on molecular drugs and therapeutic genes provides an effective
strategy for malignant tumor treatment. However, effective gene and drug combinations for …

A simple approach to synthesize new highly substituted 4 H-pyran derivatives is described.
Efficient Et3N acts as a readily accessible catalyst of this process performed in pure water …

DNA interactions with multivalent ligand (s) have increasingly become the subject of
substantial research. For several small molecules with therapeutic potential, nucleic acids …

Plasmodium parasites kill 435 000 people around the world every year due to unavailable
vaccines, a limited arsenal of antimalarial drugs, delayed treatment, and the reduced clinical …

Targeting mismatched base pairs containing DNA using small molecules and exploring the
underlying mechanism involved during the binding interactions is one of the fundamental …

Antibiotics and antibiotic resistance genes (ARGs) in the natural environment have become
substantial threats to the ecosystem and public health. Effective strategies to control …

Therapeutic applications of arsenic trioxide (ATO) are limited due to their severe adverse
effects. However, nanoparticles of ATO might possess inimitable biologic effects based on …