The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

Biophysical signals act as potent regulators of stem cell function, lineage commitment, and
epigenetic status. In recent years, synthetic biomaterials have been used to study a wide …

In vitro models of the human liver are important for the following:(1) mitigating the risk of drug-
induced liver injury to human beings,(2) modeling human liver diseases,(3) elucidating the …

Background The DNA methylation profiles of mammalian cell lines differ from those of the
primary tissues from which they were derived, exhibiting increasing divergence from the in …

Many existing clinical treatments are limited in their ability to completely restore decreased
or lost tissue and organ function, an unenviable situation only further exacerbated by a …

Cultures of human embryonic stem cell typically rely on protein matrices or feeder cells to
support attachment and growth, while mechanical, enzymatic or chemical cell dissociation …

Technologies for measuring physiological parameters in vivo offer the possibility of the
detection of disease and its progression due to the resulting changes in tissue pH, or …

Maintaining stable differentiated somatic cell function in culture is essential to a range of
biological endeavors. However, current technologies, employing, for example, primary …

A new class of material resistant to bacterial attachment has been discovered that is formed
from polyacrylates with hydrocarbon pendant groups. In this study, the relationship between …

Tissue engineering tools and technologies are critical for regenerative medicine and the
translational research supporting development of cell-based therapies. 3D cell bioprinting is …