Several lines of preclinical and clinical research have confirmed that chronic low-grade
inflammation of adipose tissue is mechanistically linked to metabolic disease and organ …

Hypertension affects approximately one third of the world's adult population and is a major
cause of premature death despite considerable advances in pharmacological treatments …

The objective of this comprehensive review is to summarize and discuss the available
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …

Summary Although 5%–10% weight loss is routinely recommended for people with obesity,
the precise effects of 5% and further weight loss on metabolic health are unclear. We …

Abstract The Biomarkers of Nutrition for Development (BOND) project is designed to provide
evidence-based advice to anyone with an interest in the role of nutrition in health …

Mechanisms of Glucocorticoid-Induced Insulin Resistance - Endocrinology and Metabolism
Clinics Skip to Main Content Skip to Main Menu Advertisement Endocrinology and …

Dieting is the most common approach to losing weight for the majority of obese and
overweight individuals. Restricting intake leads to weight loss in the short term, but, by itself …

Obesity elicits an immune response characterized by myeloid cell recruitment to key
metabolic organs, including adipose tissue. However, the response of immune cells to …

Physical activity and exercise are key components of energy expenditure and therefore of
energy balance. Changes in energy balance alter fat mass. It is therefore reasonable to ask …

One of the biggest challenges in the management of obesity is the prevention of weight
regain after successful weight loss. Weight regain after weight loss has large interindividual …