Toxoplasma gondii (T. gondii) is a prevalent protozoan parasite of medical and veterinary
significance. It is the etiologic agent of toxoplasmosis, a neglected disease in which …

Toxoplasmosis is a unique health disease that significantly affects the health of humans,
domestic animals, wildlife and is present in ecosystems, including water, soil and food …

The remarkable discovery of small noncoding microRNAs (miRNAs) and their role in
posttranscriptional gene regulation have revealed another fine-tuning step in the expression …

RNA interference (RNAi) pathways are widespread in metaozoans but the genes required
show variable occurrence or activity in eukaryotic microbes, including many pathogens …

After invading host cells, Toxoplasma gondii multiplies within a parasitophorous vacuole
(PV) that is maintained by parasite proteins secreted from organelles called dense granules …

Protozoan parasites that profoundly affect mankind represent an exceptionally diverse group
of organisms, including Plasmodium, Toxoplasma, Entamoeba, Giardia, trypanosomes, and …

In eukaryotic organisms, noncoding RNAs (ncRNAs) have been implicated as important
regulators of multifaceted biological processes, including transcriptional, posttranscriptional …

Background Gene expression is controlled at multiple levels, including transcription,
stability, translation, and degradation. Over the years, it has become apparent that …

MicroRNAs (miRNAs) are a class of small, non-coding RNAs that regulate gene expression
in eukaryotic cells. The past decade has seen an explosion in our understanding of the sets …

Tachyzoite to bradyzoite development in Toxoplasma is marked by major changes in gene
expression resulting in a parasite that expresses a new repertoire of surface antigens …