Silk biomaterials in wound healing and skin regeneration therapeutics: From bench to bedside

D Chouhan, BB Mandal - Acta biomaterialia, 2020 - Elsevier
Silk biomaterials are known for biomedical and tissue engineering applications including
drug delivery and implantable devices owing to their biocompatible and a wide range of …

[HTML][HTML] Solid implantable devices for sustained drug delivery

E Magill, S Demartis, E Gavini, AD Permana… - Advanced Drug Delivery …, 2023 - Elsevier
Implantable drug delivery systems (IDDS) are an attractive alternative to conventional drug
administration routes. Oral and injectable drug administration are the most common routes …

Graphene oxide: An efficient material and recent approach for biotechnological and biomedical applications

DP Singh, CE Herrera, B Singh, S Singh… - Materials Science and …, 2018 - Elsevier
Abstract The two-dimensional (2D) derivative of graphite termed graphene has widespread
applications in various frontiers areas of nanoscience and nanotechnologies. Graphene in …

Metal− Organic Frameworks Nucleated by Silk Fibroin and Modified with Tumor‐Targeting Peptides for Targeted Multimodal Cancer Therapy

Y Chen, R Lyu, J Wang, Q Cheng, Y Yu… - Advanced …, 2023 - Wiley Online Library
Multimodal therapy requires effective drug carriers that can deliver multiple drugs to specific
locations in a controlled manner. Here, the study presents a novel nanoplatform constructed …

Biopolymers for antitumor implantable drug delivery systems: recent advances and future outlook

S Talebian, J Foroughi, SJ Wade, KL Vine… - Advanced …, 2018 - Wiley Online Library
In spite of remarkable improvements in cancer treatments and survivorship, cancer still
remains as one of the major causes of death worldwide. Although current standards of care …

Doxorubicin-loaded magnetic silk fibroin nanoparticles for targeted therapy of multidrug-resistant cancer.

Y Tian, X Jiang, X Chen, Z Shao… - … Materials (Deerfield Beach …, 2014 - europepmc.org
A strategy to prepare doxorubicin-loaded magnetic silk fibroin nanoparticles is presented.
The nanoparticles serve as a nanometer-scale drug-delivery system in the chemotherapy of …

Injectable and pH-responsive silk nanofiber hydrogels for sustained anticancer drug delivery

H Wu, S Liu, L Xiao, X Dong, Q Lu… - ACS applied materials & …, 2016 - ACS Publications
Silk is useful as a drug carrier due to its biocompatibility, tunable degradation, and
outstanding capacity in maintaining the function of drugs. Injectable silk hydrogels could …

Biomaterial-based regional chemotherapy: Local anticancer drug delivery to enhance chemotherapy and minimize its side-effects

K Krukiewicz, JK Zak - Materials Science and Engineering: C, 2016 - Elsevier
Since the majority of anticancer pharmacological agents affect not only cancer tissue but
also normal cells, chemotherapy is usually accompanied with severe side effects. Regional …

pH‐dependent anticancer drug release from silk nanoparticles

FP Seib, GT Jones, J Rnjak‐Kovacina… - Advanced …, 2013 - Wiley Online Library
Silk has traditionally been used as a suture material because of its excellent mechanical
properties and biocompatibility. These properties have led to the development of different …

Delivering on the promise of recombinant silk-inspired proteins for drug delivery

C Gonzalez-Obeso, EJ Hartzell, RA Scheel… - Advanced drug delivery …, 2023 - Elsevier
Effective drug delivery is essential for the success of a medical treatment. Polymeric drug
delivery systems (DDSs) are preferred over systemic administration of drugs due to their …