Immunomodulatory biomaterials for tissue repair

R Whitaker, B Hernaez-Estrada… - Chemical …, 2021 - ACS Publications
All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

Combating implant infections: shifting focus from bacteria to host

S Amin Yavari, SM Castenmiller… - Advanced …, 2020 - Wiley Online Library
The widespread use of biomaterials to support or replace body parts is increasingly
threatened by the risk of implant‐associated infections. In the quest for finding novel anti …

Functionalized helical fibre bundles of carbon nanotubes as electrochemical sensors for long-term in vivo monitoring of multiple disease biomarkers

L Wang, S Xie, Z Wang, F Liu, Y Yang, C Tang… - Nature Biomedical …, 2020 - nature.com
Mechanical mismatches between implanted electronics and biological tissues can lead to
inaccurate readings and long-term tissue damage. Here, we show that functionalized multi …

An overview of the role of neutrophils in innate immunity, inflammation and host-biomaterial integration

GS Selders, AE Fetz, MZ Radic… - Regenerative …, 2017 - academic.oup.com
Despite considerable recent progress in defining neutrophil functions and behaviors in
tissue repair, much remains to be determined with regards to its overall role in the tissue …

Into the tissues: Extracellular matrix and its artificial substitutes: Cell signalling mechanisms

A Bandzerewicz, A Gadomska-Gajadhur - Cells, 2022 - mdpi.com
The existence of orderly structures, such as tissues and organs is made possible by cell
adhesion, ie, the process by which cells attach to neighbouring cells and a supporting …

Immunomodulatory biomaterials for implant-associated infections: from conventional to advanced therapeutic strategies

J Dong, W Wang, W Zhou, S Zhang, M Li, N Li… - Biomaterials …, 2022 - spj.science.org
Implant-associated infection (IAI) is increasingly emerging as a serious threat with the
massive application of biomaterials. Bacteria attached to the surface of implants are often …

Key players in the immune response to biomaterial scaffolds for regenerative medicine

L Chung, DR Maestas Jr, F Housseau… - Advanced drug delivery …, 2017 - Elsevier
The compatibility of biomaterials is critical to their structural and biological function in
medical applications. The immune system is the first responder to tissue trauma and to a …

Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates

JC Doloff, O Veiseh, AJ Vegas, HH Tam, S Farah… - Nature materials, 2017 - nature.com
Host recognition and immune-mediated foreign body response to biomaterials can
compromise the performance of implanted medical devices. To identify key cell and cytokine …

Domesticating the foreign body response: Recent advances and applications

O Veiseh, AJ Vegas - Advanced drug delivery reviews, 2019 - Elsevier
The foreign body response is an immunological process that leads to the rejection of
implanted devices and presents a fundamental challenge to their performance, durability …

Wearable technology for chronic wound monitoring: current dressings, advancements, and future prospects

MS Brown, B Ashley, A Koh - Frontiers in bioengineering and …, 2018 - frontiersin.org
Chronic non-healing wounds challenge tissue regeneration and impair infection regulation
for patients afflicted with this condition. Next generation wound care technology capable of …