Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease
TJ Wadas, EH Wong, GR Weisman… - Chemical …, 2010 - ACS Publications
Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems …
processes at the molecular and cellular levels in humans and other living systems …
Copper-64 radiopharmaceuticals for PET imaging of cancer: advances in preclinical and clinical research
CJ Anderson, R Ferdani - Cancer Biotherapy and …, 2009 - liebertpub.com
Summation Copper-64 (T1/2= 12.7 hours; β+, 0.653 MeV [17.8%]; β−, 0.579 MeV [38.4%])
has decay characteristics that allow for positron emission tomography (PET) imaging and …
has decay characteristics that allow for positron emission tomography (PET) imaging and …
Copper chelation chemistry and its role in copper radiopharmaceuticals
TJ Wadas, EH Wong, GR Weisman… - Current …, 2007 - ingentaconnect.com
Molecular imaging is an important scientific discipline that plays a major role in clinical
medicine and pharmaceutical development. While several imaging modalities including X …
medicine and pharmaceutical development. While several imaging modalities including X …
Molecular imaging with copper-64
SV Smith - Journal of inorganic biochemistry, 2004 - Elsevier
Molecular imaging is expected to change the face of drug discovery and development. The
ability to link imaging to biology for guiding therapy should improve the rate at which novel …
ability to link imaging to biology for guiding therapy should improve the rate at which novel …
Gallium (III) complexes of DOTA and DOTA− monoamide: kinetic and thermodynamic studies
V Kubicek, J Havlickova, J Kotek, G Tircso… - Inorganic …, 2010 - ACS Publications
Given the practical advantages of the 68Ga isotope in positron emission tomography
applications, gallium complexes are gaining increasing importance in biomedical imaging …
applications, gallium complexes are gaining increasing importance in biomedical imaging …
Current advances in ligand design for inorganic positron emission tomography tracers 68 Ga, 64 Cu, 89 Zr and 44 Sc
TW Price, J Greenman, GJ Stasiuk - Dalton transactions, 2016 - pubs.rsc.org
A key part of the development of metal based Positron Emission Tomography probes is the
chelation of the radiometal. In this review the recent developments in the chelation of four …
chelation of the radiometal. In this review the recent developments in the chelation of four …
Kinetic Inertness and Electrochemical Behavior of Copper(II) Tetraazamacrocyclic Complexes: Possible Implications for in Vivo Stability
KS Woodin, KJ Heroux, CA Boswell, EH Wong… - 2005 - Wiley Online Library
The kinetic inertness of copper (ii) complexes of several carboxymethyl‐armed cyclams and
cyclens in 5 m HCl have been determined confirming that the complex derived from cross …
cyclens in 5 m HCl have been determined confirming that the complex derived from cross …
Complexation of metal ions with TRAP (1, 4, 7-triazacyclononane phosphinic acid) ligands and 1, 4, 7-triazacyclononane-1, 4, 7-triacetic acid: phosphinate-containing …
Three phosphinic acid 1, 4, 7-triazacyclononane (TACN) derivatives bearing
methylphosphinic (TRAP-H), methyl (phenyl) phosphinic (TRAP-Ph), or methyl …
methylphosphinic (TRAP-H), methyl (phenyl) phosphinic (TRAP-Ph), or methyl …
Monopicolinate cyclen and cyclam derivatives for stable copper (II) complexation
LMP Lima, D Esteban-Gómez, R Delgado… - Inorganic …, 2012 - ACS Publications
The syntheses of a new 1, 4, 7, 10-tetraazacyclododecane (cyclen) derivative bearing a
picolinate pendant arm (H L1), and its 1, 4, 8, 11-tetraazacyclotetradecane (cyclam) …
picolinate pendant arm (H L1), and its 1, 4, 8, 11-tetraazacyclotetradecane (cyclam) …
Synthesis, Cu (ii) complexation, 64 Cu-labeling and biological evaluation of cross-bridged cyclam chelators with phosphonate pendant arms
R Ferdani, DJ Stigers, AL Fiamengo, L Wei… - Dalton …, 2012 - pubs.rsc.org
A new class of cross-bridged cyclam-based macrocycles featuring phosphonate pendant
groups has been developed. 1, 4, 8, 11-tetraazacyclotetradecane-1, 8-di …
groups has been developed. 1, 4, 8, 11-tetraazacyclotetradecane-1, 8-di …