Spectres of clock evolution: past, present, and yet to come
ML Jabbur, CH Johnson - Frontiers in Physiology, 2022 - frontiersin.org
Circadian clocks are phylogenetically widespread biological oscillators that allow organisms
to entrain to environmental cycles and use their steady-state phase relationship to anticipate …
to entrain to environmental cycles and use their steady-state phase relationship to anticipate …
Adaptive laboratory evolution of microorganisms: Methodology and application for bioproduction
T Hirasawa, T Maeda - Microorganisms, 2022 - mdpi.com
Adaptive laboratory evolution (ALE) is a useful experimental methodology for fundamental
scientific research and industrial applications to create microbial cell factories. By using ALE …
scientific research and industrial applications to create microbial cell factories. By using ALE …
Changing fitness effects of mutations through long-term bacterial evolution
The distribution of fitness effects of new mutations shapes evolution, but it is challenging to
observe how it changes as organisms adapt. Using Escherichia coli lineages spanning …
observe how it changes as organisms adapt. Using Escherichia coli lineages spanning …
Long-term experimental evolution decouples size and production costs in Escherichia coli
Body size covaries with population dynamics across life's domains. Metabolism may impose
fundamental constraints on the coevolution of size and demography, but experimental tests …
fundamental constraints on the coevolution of size and demography, but experimental tests …
Evolutionary scaling of maximum growth rate with organism size
M Lynch, B Trickovic, CP Kempes - Scientific reports, 2022 - nature.com
Data from nearly 1000 species reveal the upper bound to rates of biomass production
achievable by natural selection across the Tree of Life. For heterotrophs, maximum growth …
achievable by natural selection across the Tree of Life. For heterotrophs, maximum growth …
What programs the size of animal cells?
The human body is programmed with definite quantities, magnitudes, and proportions. At the
microscopic level, such definite sizes manifest in individual cells-different cell types are …
microscopic level, such definite sizes manifest in individual cells-different cell types are …
In vivo, in vitro and in silico: an open space for the development of microbe‐based applications of synthetic biology
A Danchin - Microbial Biotechnology, 2022 - Wiley Online Library
Living systems are studied using three complementary approaches: living cells, cell‐free
systems and computer‐mediated modelling. Progresses in understanding, allowing …
systems and computer‐mediated modelling. Progresses in understanding, allowing …
Case studies in the assessment of microbial fitness: seemingly subtle changes can have major effects on phenotypic outcomes
SB Worthan, RDP McCarthy, MG Behringer - Journal of Molecular …, 2023 - Springer
Following the completion of an adaptive evolution experiment, fitness evaluations are
routinely conducted to assess the magnitude of adaptation. In doing so, proper …
routinely conducted to assess the magnitude of adaptation. In doing so, proper …
Expanding the upper‐temperature boundary for the microalga Picochlorum sp. (BPE23) by adaptive laboratory evolution
R Barten, T Peeters, S Navalho… - Biotechnology …, 2022 - Wiley Online Library
Closed photobioreactors reach temperatures that reduce microalgal production or even
cause culture collapses. Cooling can maintain the temperature within tolerable boundaries …
cause culture collapses. Cooling can maintain the temperature within tolerable boundaries …
'Evolutionary poker': an agent‐based model of interactome emergence and epistasis tested against Lenski's long‐term E. coli experiments
RS Root‐Bernstein, MI Bernstein - The Journal of Physiology, 2024 - Wiley Online Library
A simple agent‐based model is presented that produces results matching the experimental
data found by Lenski's group for≤ 50,000 generations of Escherichia coli bacteria under …
data found by Lenski's group for≤ 50,000 generations of Escherichia coli bacteria under …