Microbiota-mediated colonization resistance: mechanisms and regulation

G Caballero-Flores, JM Pickard, G Núñez - Nature Reviews …, 2023 - nature.com
A dense and diverse microbial community inhabits the gut and many epithelial surfaces.
Referred to as the microbiota, it co-evolved with the host and is beneficial for many host …

The Diversity of Escherichia coli Pathotypes and Vaccination Strategies against This Versatile Bacterial Pathogen

P Pokharel, S Dhakal, CM Dozois - Microorganisms, 2023 - mdpi.com
Escherichia coli (E. coli) is a gram-negative bacillus and resident of the normal intestinal
microbiota. However, some E. coli strains can cause diseases in humans, other mammals …

[HTML][HTML] The microbiota coordinates diurnal rhythms in innate immunity with the circadian clock

JF Brooks, CL Behrendt, KA Ruhn, S Lee, P Raj… - Cell, 2021 - cell.com
Environmental light cycles entrain circadian feeding behaviors in animals that produce
rhythms in exposure to foodborne bacteria. Here, we show that the intestinal microbiota …

[HTML][HTML] Iron in infection and immunity

M Nairz, G Weiss - Molecular Aspects of Medicine, 2020 - Elsevier
Iron is an essential micronutrient for virtually all living cells. In infectious diseases, both
invading pathogens and mammalian cells including those of the immune system require iron …

Interactions between the microbiota and pathogenic bacteria in the gut

AJ Bäumler, V Sperandio - Nature, 2016 - nature.com
The microbiome has an important role in human health. Changes in the microbiota can
confer resistance to or promote infection by pathogenic bacteria. Antibiotics have a profound …

Salmonella versus the Microbiome

AWL Rogers, RM Tsolis… - … and Molecular Biology …, 2021 - Am Soc Microbiol
SUMMARY A balanced gut microbiota contributes to health, but the mechanisms
maintaining homeostasis remain elusive. Microbiota assembly during infancy is governed by …

[HTML][HTML] Iron in immune cell function and host defense

D Haschka, A Hoffmann, G Weiss - Seminars in Cell & Developmental …, 2021 - Elsevier
The control over iron availability is crucial under homeostatic conditions and even more in
the case of an infection. This results from diverse properties of iron: first, iron is an important …

The role of iron in host–microbiota crosstalk and its effects on systemic glucose metabolism

J Mayneris-Perxachs, JM Moreno-Navarrete… - Nature Reviews …, 2022 - nature.com
Iron is critical for the appearance and maintenance of life on Earth. Almost all organisms
compete or cooperate for iron acquisition, demonstrating the importance of this essential …

Microcins mediate competition among Enterobacteriaceae in the inflamed gut

M Sassone-Corsi, SP Nuccio, H Liu, D Hernandez… - Nature, 2016 - nature.com
The Enterobacteriaceae are a family of Gram-negative bacteria that include commensal
organisms as well as primary and opportunistic pathogens that are among the leading …

[HTML][HTML] How bacterial pathogens colonize their hosts and invade deeper tissues

D Ribet, P Cossart - Microbes and infection, 2015 - Elsevier
Bacterial pathogens have evolved a wide range of strategies to colonize and invade human
organs, despite the presence of multiple host defense mechanisms. In this review, we will …