The corpus luteum is an endocrine gland that synthesizes the steroid hormone
progesterone. luteinizing hormone (LH) is a key luteotropic hormone that stimulates …

Cell lines as an in vitro model for xenobiotic screening and toxicity studies provide a very
important tool in the field of scientific research at the level of molecular pathways and gene …

Luteinizing hormone (LH) via protein kinase A (PKA) triggers ovulation and formation of the
corpus luteum, which arises from the differentiation of follicular granulosa and theca cells …

Progesterone is an essential steroid hormone that is required to initiate and maintain
pregnancy in mammals and serves as a metabolic intermediate in the synthesis of …

Research question: Theca interna cells (TICs) are an indispensable cell source for ovarian
follicle development and steroidogenesis. Recent studies have identified theca stem cells …

Lipid droplets (LDs) are endoplasmic reticulum (ER)-derived organelles comprising a core
of neutral lipids surrounded by a phospholipid monolayer. Lipid droplets play important roles …

Background Metabolic stress, as negative energy balance on one hand or obesity on the
other hand can lead to increased levels of free fatty acids in the plasma and follicular fluid of …

Corpus luteum (CL), a transitory gland, undergoes rapid growth in a limited time to produce
progesterone (P4) followed by its regression. A complex molecular signaling is involved in …

In the absence of pregnancy the ovarian corpus luteum undergoes regression, a process
characterized by decreased production of progesterone and structural luteolysis involving …

Stearoyl-CoA desaturase (SCD) is a key enzyme catalyzing the rate-limiting step in
monounsaturated fatty acids (MUFAs) production. There may be a mechanism by which …