To commemorate the auspicious occasion of the 30th anniversary of IPC, leading pioneers
in the field of cardioprotection gathered in Barcelona in May 2016 to review and discuss the …

Abstract Sphingosine-1-phosphate (S1P) is a signaling lipid, synthetized by sphingosine
kinases (SPHK1 and SPHK2), that affects cardiovascular function in various ways. S1P …

Ischemia–reperfusion injury (IRI) is one of the biggest challenges for cardiovascular
researchers given the huge death toll caused by myocardial ischemic disease …

Ischaemic pre‐and postconditioning are potent cardioprotective interventions that spare
ischaemic myocardium and decrease infarct size after periods of myocardial …

The survivor activating factor enhancement (SAFE) pathway was discovered as an
alternative intrinsic pro-survival signaling pathway to the reperfusion injury salvage kinase …

Lowered high-density lipoprotein (HDL) cholesterol has been reported in major depressive
disorder, bipolar disorder, first episode of psychosis, and schizophrenia. HDL, its major …

High-density lipoprotein cholesterol (HDL-C) has been identified as a powerful independent
negative predictor of cardiovascular disease. The beneficial effect of HDL is largely …

The cholesterol concentrations of low-density lipoprotein (LDL) and high-density lipoprotein
(HDL) have traditionally served as risk factors for cardiovascular disease. As such, novel …

Objective—The dyslipidemia of type 2 diabetes mellitus has multiple etiologies and impairs
lipoprotein functionality, thereby increasing risk for cardiovascular disease. High-density …

Since the discovery of ischemic pre-and post-conditioning, more than 30 years ago, the
knowledge about the mechanisms and signaling pathways involved in these processes has …