Interpreting the language of histone and DNA modifications
SB Rothbart, BD Strahl - Biochimica et Biophysica Acta (BBA)-Gene …, 2014 - Elsevier
A major mechanism regulating the accessibility and function of eukaryotic genomes are the
covalent modifications to DNA and histone proteins that dependably package our genetic …
covalent modifications to DNA and histone proteins that dependably package our genetic …
[HTML][HTML] Navigating the DNA methylation landscape of cancer
A Nishiyama, M Nakanishi - Trends in Genetics, 2021 - cell.com
DNA methylation is a chemical modification that defines cell type and lineage through the
control of gene expression and genome stability. Disruption of DNA methylation control …
control of gene expression and genome stability. Disruption of DNA methylation control …
Establishing, maintaining and modifying DNA methylation patterns in plants and animals
JA Law, SE Jacobsen - Nature Reviews Genetics, 2010 - nature.com
Cytosine DNA methylation is a stable epigenetic mark that is crucial for diverse biological
processes, including gene and transposon silencing, imprinting and X chromosome …
processes, including gene and transposon silencing, imprinting and X chromosome …
[HTML][HTML] Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells
H Otera, C Wang, MM Cleland, K Setoguchi… - The Journal of cell …, 2010 - ncbi.nlm.nih.gov
The cytoplasmic dynamin-related guanosine triphosphatase Drp1 is recruited to
mitochondria and mediates mitochondrial fission. Although the mitochondrial outer …
mitochondria and mediates mitochondrial fission. Although the mitochondrial outer …
DNA methyltransferases, DNA damage repair, and cancer
B Jin, KD Robertson - Epigenetic alterations in oncogenesis, 2012 - Springer
The maintenance DNA methyltransferase (DNMT) 1 and the de novo methyltransferases
DNMT3A and DNMT3B are all essential for mammalian development. DNA methylation …
DNMT3A and DNMT3B are all essential for mammalian development. DNA methylation …
[HTML][HTML] Specific or not specific recruitment of DNMTs for DNA methylation, an epigenetic dilemma
E Hervouet, P Peixoto, R Delage-Mourroux… - Clinical …, 2018 - Springer
Our current view of DNA methylation processes is strongly moving: First, even if it was
generally admitted that DNMT3A and DNMT3B are associated with de novo methylation and …
generally admitted that DNMT3A and DNMT3B are associated with de novo methylation and …
Staying true to yourself: mechanisms of DNA methylation maintenance in mammals
DNA methylation is essential to development and cellular physiology in mammals. Faulty
DNA methylation is frequently observed in human diseases like cancer and neurological …
DNA methylation is frequently observed in human diseases like cancer and neurological …
Chromatin structure and the inheritance of epigenetic information
R Margueron, D Reinberg - Nature Reviews Genetics, 2010 - nature.com
Although it is widely accepted that the regulation of the chromatin landscape is pivotal to
conveying the epigenetic program, it is still unclear how a defined chromatin domain is …
conveying the epigenetic program, it is still unclear how a defined chromatin domain is …
[HTML][HTML] Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands
HM O'Hagan, W Wang, S Sen, CDS Shields, SS Lee… - Cancer cell, 2011 - cell.com
Cancer cells simultaneously harbor global losses and gains in DNA methylation. We
demonstrate that inducing cellular oxidative stress by hydrogen peroxide treatment recruits …
demonstrate that inducing cellular oxidative stress by hydrogen peroxide treatment recruits …
Rethinking how DNA methylation patterns are maintained
DNA methylation patterns are set up early in mammalian development and are then copied
during the division of somatic cells. A long-established model for the maintenance of these …
during the division of somatic cells. A long-established model for the maintenance of these …