Polypharmacy is very common in older adults and increases the risk of inappropriate and
unsafe prescribing for older adults. Older adults, particularly women (who make up the …

Background The cumulative effect of taking multiple medicines with anticholinergic
properties termed as anticholinergic burden can adversely impact cognition, physical …

Aim The aim was to investigate associations between drugs with anticholinergic effects
(DACEs) and cognitive impairment, falls and all‐cause mortality in older adults. Methods A …

People are living to older age. Falls constitute a leading cause of injuries, hospitalization
and deaths among the elderly. Older people fall more often for a variety of reasons …

Background Polypharmacy and potentially inappropriate medications (PIMs) are prevalent
in older adults in hospital, and are associated with negative outcomes including adverse …

Objectives Deprescribing has been proposed as a way to reduce polypharmacy in frail older
people. We aimed to reduce the number of medicines consumed by people living in …

Context The cognitive side effects of medications with anticholinergic activity have been
documented among older adults in a variety of clinical settings. However, there has been no …

Background Older people taking multiple medications represent a large and growing
proportion of the population. Managing multiple medications can be challenging, and this is …

This study examined the relation between sleep quality and cognitive performance in older
adults, controlling for common medical comorbidities. Participants were community …

Evidence about the association between treatment with high–risk medicines and frailty in
older individuals is limited. We investigated the relationship between high–risk prescribing …