Pharmacologic resistance in colorectal cancer: a review

WA Hammond, A Swaika… - Therapeutic advances in …, 2016 - journals.sagepub.com
Colorectal cancer (CRC) persists as one of the most prevalent and deadly tumor types in
both men and women worldwide. This is in spite of widespread, effective measures of …

Biochemical markers of colorectal cancer–present and future

W Jelski, B Mroczko - Cancer management and research, 2020 - Taylor & Francis
According to a report by the National Cancer Institute, colorectal cancer (CRC) is one of the
most common types of cancer worldwide. CRC is often recognized too late for successful …

G protein-coupled receptors as promising cancer targets

Y Liu, S An, R Ward, Y Yang, XX Guo, W Li, TR Xu - Cancer letters, 2016 - Elsevier
G protein-coupled receptors (GPCRs) regulate an array of fundamental biological
processes, such as growth, metabolism and homeostasis. Specifically, GPCRs are involved …

Bombesin related peptides/receptors and their promising therapeutic roles in cancer imaging, targeting and treatment

P Moreno, I Ramos-Álvarez, TW Moody… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Despite remarkable advances in tumor treatment, many patients still die from
common tumors (breast, prostate, lung, CNS, colon, and pancreas), and thus, new …

[HTML][HTML] Recent innovations in peptide based targeted drug delivery to cancer cells

Y Gilad, M Firer, G Gellerman - Biomedicines, 2016 - mdpi.com
Targeted delivery of chemotherapeutics and diagnostic agents conjugated to carrier ligands
has made significant progress in recent years, both in regards to the structural design of the …

[HTML][HTML] Upregulated SLC1A5 promotes cell growth and survival in colorectal cancer

F Huang, Y Zhao, J Zhao, S Wu, Y Jiang… - … journal of clinical and …, 2014 - ncbi.nlm.nih.gov
Glutamine metabolism is essential for tumorigenesis of colorectal cancer, cancer cells
remodel their glutamine metabolic pathways to fuel rapid proliferation. SLC1A5 is an …

NPTX1 inhibits colon cancer cell proliferation through down‐regulating cyclin A2 and CDK2 expression

X Peng, K Pan, W Zhao, J Zhang, S Yuan… - Cell biology …, 2018 - Wiley Online Library
Colon cancer is the third most common malignancy and one of the leading causes of cancer‐
associated mortality worldwide. Neuronal pentraxin 1 (NPTX1) is associated with tumor …

Management and grading of EGFR inhibitor-induced cutaneous toxicity

J Beech, T Germetaki, M Judge, N Paton… - Future …, 2018 - Taylor & Francis
Cutaneous toxicities associated with EGFR inhibitors (EGFRIs) have a significant impact on
patient treatment continuation, quality of life and healthcare resource utilization. This paper …

An update on the potential roles of E2F family members in colorectal cancer

ZH Xu, H Qu, YY Ren, ZZ Gong, HJ Ri… - Cancer management …, 2021 - Taylor & Francis
Colorectal cancer (CRC) is a major health burden worldwide, and thus, optimised diagnosis
and treatments are imperative. E2F transcription factors (E2Fs) are a family of transcription …

[HTML][HTML] Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6

N Golob-Schwarzl, C Schweiger, C Koller, S Krassnig… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most common cause of cancer related death worldwide.
Furthermore, with more than 1.2 million cases registered per year, it constitutes the third …