Hair follicle immune privilege and its collapse in alopecia areata

M Bertolini, K McElwee, A Gilhar… - Experimental …, 2020 - Wiley Online Library
Anagen stage hair follicles (HFs) exhibit “immune privilege (IP)” from the level of the bulge
downwards to the bulb. Both passive and active IP mechanisms protect HFs from …

Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation

M Wu, LJ Hill, LE Downie, HR Chinnery - Progress in Retinal and Eye …, 2022 - Elsevier
In the cornea, resident immune cells are in close proximity to sensory nerves, consistent with
their important roles in the maintenance of nerves in both homeostasis and inflammation …

Keratoplasty rejection after the BNT162b2 messenger RNA vaccine

LM Wasser, E Roditi, D Zadok, L Berkowitz, Y Weill - Cornea, 2021 - journals.lww.com
Purpose: The aim of this report was to report 2 patients who presented with acute corneal
graft rejection 2 weeks after receiving the BNT162b2 messenger RNA (mRNA) vaccine for …

[HTML][HTML] Resident innate immune cells in the cornea

J Liu, Z Li - Frontiers in immunology, 2021 - frontiersin.org
The cornea is a special interface between the internal ocular tissue and the external
environment that provides a powerful chemical, physical, and biological barrier against the …

The two-faced effects of nerves and neuropeptides in corneal diseases

RML Vitar, P Rama, G Ferrari - Progress in Retinal and Eye Research, 2022 - Elsevier
Corneal nerves are instrumental to maintain cornea integrity through regulation of key
physiological functions such as tear secretion, blink reflex, and neuropeptide turnover …

Innate immune response in retinal homeostasis and inflammatory disorders

Y Murakami, K Ishikawa, S Nakao… - Progress in retinal and eye …, 2020 - Elsevier
Innate immune cells such as neutrophils, monocyte-macrophages and microglial cells are
pivotal for the health and disease of the retina. For the maintenance of retinal homeostasis …

[HTML][HTML] Macrophage-mediated tissue vascularization: similarities and differences between cornea and skin

K Hadrian, S Willenborg, F Bock, C Cursiefen… - Frontiers in …, 2021 - frontiersin.org
Macrophages are critical mediators of tissue vascularization both in health and disease. In
multiple tissues, macrophages have been identified as important regulators of both blood …

[HTML][HTML] Immunomodulatory role of neuropeptides in the cornea

S Puri, BM Kenyon, P Hamrah - Biomedicines, 2022 - mdpi.com
The transparency of the cornea along with its dense sensory innervation and resident
leukocyte populations make it an ideal tissue to study interactions between the nervous and …

Corneal transplantation in the aftermath of the COVID-19 pandemic: an international perspective

M Ang, A Moriyama, K Colby, G Sutton… - British Journal of …, 2020 - bjo.bmj.com
Corneal blindness is the third leading cause of blindness worldwide. 1 Corneal
transplantation remains the only method of restoring vision in eyes with end-stage corneal …

[HTML][HTML] Immune privilege of heart valves

MA Hill, JH Kwon, B Gerry, WA Hardy… - Frontiers in …, 2021 - frontiersin.org
Immune privilege is an evolutionary adaptation that protects vital tissues with limited
regenerative capacity from collateral damage by the immune response. Classical examples …