Tetracyclines constitute a unique class of antibiotic agents, widely prescribed for both
community and hospital infections due to their broad spectrum of activity. Acting by …

Klebsiella pneumoniae is a common opportunistic pathogen that presents significant
challenges in the treatment of infections due to its resistance to multiple antibiotics. In recent …

This study aimed to determine the proportion of heteroresistance in carbapenem-resistant
Acinetobacter calcoaceticus-baumannii complex (CRAB) isolates in the cefiderocol arm of …

Colistin heteroresistance (HR) refers to a bacterial population comprised of several
subpopulations with different levels of resistance to colistin. In this study, we discuss the …

The drug resistance of bacterial pathogens causes considerable morbidity and death
globally, hence there is a crucial necessity for the development of effective antibacterial …

We reviewed the literature of last 20 years and found a limited number of studies evaluating
the relationship between heteroresistance and clinical outcome in nonfermenting GNB …

Objectives To study the clinical relevance, mechanisms, and evolution of polymyxin B
(POLB) heteroresistance (PHR) in carbapenem-resistant Klebsiella pneumoniae (CRKP) …

Novel therapeutic strategies against difficult-to-treat bacterial infections are desperately
needed, and the faster and cheaper way to get them might be by repurposing existing …

The ESKAPE pathogens, including bacteria such as Enterococcus faecium, Staphylococcus
aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and …

Colistin heteroresistance has been identified in several bacterial species, including
Escherichia coli and Klebsiella pneumoniae, and may underlie antibiotic therapy failures …