Heart valves are essential for maintaining unidirectional blood flow, and their failure can
severely affect cardiac functions. The use of artificial heart valves as replacement has …

Background Acute dysfunction of mechanical aortic valve prostheses is a life-threatening
adverse event. Pannus overgrowth, which is fibroelastic hyperplasia originating from the …

Pannus-related prosthetic valve dysfunction, a complication of mechanical prosthetic valve
replacement, is rare, with a slowly progressive evolution, but it can be acute, severe …

Some patients with a bileaflet mechanical heart valve (BMHV) show significant increases in
the transvalvular pressure drop and abnormal leaflet motion due to a pannus (an abnormal …

Objective: Pannus overgrowth is a chronic inflammatory process that can cause valve
dysfunction and threaten the durability of prosthetic valves. Bileaflet mechanical mitral valve …