In the last two decades, multi (MDR), extensively (XDR), extremely (XXDR) and total (TDR)
drug-resistant Mycobacterium tuberculosis (M. tb) strains have emerged as a threat to public …

Genomics and bioinformatics are increasingly contributing to our understanding of infectious
diseases caused by bacterial pathogens such as Mycobacterium tuberculosis and parasites …

Macrophages are the preferential cell types to study various aspects of mycobacterial
infection. Commonly used infection models for in-vitro studies are primary macrophages …

Abstract The 2′, 5′(OASs) are known as mediators of the antiviral response system
through activation of the RNA cleavage pathway. Interestingly, we observe OAS1, OAS2 and …

Tuberculosis (TB) is currently the number one killer among infectious diseases worldwide.
Lipids are abundant molecules during the infectious cycle of Mycobacterium tuberculosis …

The rough morphotypes of non-tuberculous mycobacteria have been associated with the
most severe illnesses in humans. This idea is consistent with the fact that Mycobacterium …

The causative agent of tuberculosis, Mycobacterium tuberculosis, shares several
characteristics with organisms that produce biofilms during infections. One of these is the …

As a means to increase the growth rate and reduce aggregation, Tween 80 is routinely
added to growth media during mycobacterial culturing. This detergent has, however, been …

Abstract Background The function of Toll-like receptor 2 (TLR2) in host defense against
pathogens, especially Mycobacterium tuberculosis (Mtb) is poorly understood. To …

Despite their high degree of genomic similarity, different spotted fever group (SFG)
Rickettsia are often associated with very different clinical presentations. For example …