Diabetic peripheral neuropathy: advances in diagnosis and strategies for screening and early intervention

D Selvarajah, D Kar, K Khunti, MJ Davies… - The lancet Diabetes & …, 2019 - thelancet.com
Diabetic peripheral neuropathy (DPN) is a common complication of both type 1 and 2
diabetes. It is a leading cause of lower-limb amputation and disabling neuropathic pain …

Global mortality of diabetic foot ulcer: a systematic review and meta‐analysis of observational studies

L Chen, S Sun, Y Gao, X Ran - Diabetes, Obesity and …, 2023 - Wiley Online Library
Aim To estimate the long‐term mortality and risk factors in patients with diabetic foot ulcer
(DFU). Methods We systematically searched Medline (PubMed), Embase, Scopus, Web of …

Five year mortality and direct costs of care for people with diabetic foot complications are comparable to cancer

DG Armstrong, MA Swerdlow, AA Armstrong… - Journal of foot and ankle …, 2020 - Springer
Background In 2007, we reported a summary of data comparing diabetic foot complications
to cancer. The purpose of this brief report was to refresh this with the best available data as …

Wound-healing effects of curcumin and its nanoformulations: a comprehensive review

A Kumari, N Raina, A Wahi, KW Goh, P Sharma… - Pharmaceutics, 2022 - mdpi.com
Wound healing is an intricate process of tissue repair or remodeling that occurs in response
to injury. Plants and plant-derived bioactive constituents are well explored in the treatment of …

Diabetes and wound angiogenesis

UA Okonkwo, LA DiPietro - International journal of molecular sciences, 2017 - mdpi.com
Diabetes Mellitus Type II (DM2) is a growing international health concern with no end in
sight. Complications of DM2 involve a myriad of comorbidities including the serious …

Association of diabetic foot ulcer and death in a population‐based cohort from the United Kingdom

JW Walsh, OJ Hoffstad, MO Sullivan… - Diabetic …, 2016 - Wiley Online Library
Aims The presence of diabetic foot ulcers is strongly associated with an increased risk of
death. In this study, we investigate whether the effects of diabetes‐associated complications …

Strain-and species-level variation in the microbiome of diabetic wounds is associated with clinical outcomes and therapeutic efficacy

LR Kalan, JS Meisel, MA Loesche, J Horwinski… - Cell host & …, 2019 - cell.com
Chronic wounds are a major complication of diabetes associated with high morbidity and
health care expenditures. To investigate the role of colonizing microbiota in diabetic wound …

Incidence and risk factors of diabetic foot ulcer: a population‐based diabetic foot cohort (ADFC study)—two‐year follow‐up study

L Yazdanpanah, H Shahbazian, I Nazari… - International journal …, 2018 - Wiley Online Library
Aim/Introduction. This study was carried out to assess the incidence and risk factors of
diabetic foot ulcer (DFU). Materials and Methods. In this prospective cohort study in a …

Compromised angiogenesis and vascular Integrity in impaired diabetic wound healing

UA Okonkwo, L Chen, D Ma, VA Haywood, M Barakat… - PloS one, 2020 - journals.plos.org
Vascular deficits are a fundamental contributing factor of diabetes-associated diseases.
Although previous studies have demonstrated that the pro-angiogenic phase of wound …

Long term outcomes after incident diabetic foot ulcer: Multicenter large cohort prospective study (EDI-FOCUS investigators) epidemiology of diabetic foot …

A Rastogi, G Goyal, R Kesavan, A Bal, H Kumar… - Diabetes research and …, 2020 - Elsevier
Aims This long-term prospective study evaluated limb amputation and mortality after the first
neuropathic diabetic foot ulcer (DFU). Methods A total of 2880 patients with neuropathic …