Abstract The Sequence Alignment/Map (SAM) format file is the text file used to record
alignment information. Alignment is the core of sequencing analysis, and downstream tasks …

Post-Sanger sequencing methods produce tons of data, and there is a generalagreement
that the challenge to store and process them must be addressedwith data compression. In …

Storage and transmission of the data produced by modern DNA sequencing instruments has
become a major concern, which prompted the Pistoia Alliance to pose the …

Current genomics data formats and processing pipelines are not designed to scale well to
large datasets. The current Sequence/Binary Alignment/Map (SAM/BAM) formats were …

The ever increasing growth of the production of high-throughput sequencing data poses a
serious challenge to the storage, processing and transmission of these data. As frequently …

Motivation: The data deluge phenomenon is becoming a serious problem in most genomic
centers. To alleviate it, general purpose tools, such as gzip, are used to compress the data …

The long-term storage of the batteries' operating data is critical to tracing and analysing their
historical use but challenged by the Trillions of bytes of raw data generated per day. For …

The exponential growth of high-throughput DNA sequence data has posed great challenges
to genomic data storage, retrieval and transmission. Compression is a critical tool to address …

Recently, there has been growing interest in genome sequencing, driven by advances in
sequencing technology, in terms of both efficiency and affordability. These developments …

Motivation: Genomic repositories are rapidly growing, as witnessed by the 1000 Genomes or
the UK10K projects. Hence, compression of multiple genomes of the same species has …