Physiological and functional basis of dopamine receptors and their role in neurogenesis: possible implication for Parkinson's disease
Dopamine controls various physiological functions in the brain and periphery by acting on its
receptors D1, D2, D3, D4, and D5. Dopamine receptors are G protein–coupled receptors …
receptors D1, D2, D3, D4, and D5. Dopamine receptors are G protein–coupled receptors …
Clinical proton MR spectroscopy in central nervous system disorders
A large body of published work shows that proton (hydrogen 1 [1H]) magnetic resonance
(MR) spectroscopy has evolved from a research tool into a clinical neuroimaging modality …
(MR) spectroscopy has evolved from a research tool into a clinical neuroimaging modality …
A genetically encoded fluorescent sensor for in vivo imaging of GABA
Current techniques for monitoring GABA (γ-aminobutyric acid), the primary inhibitory
neurotransmitter in vertebrates, cannot follow transients in intact neural circuits. To develop …
neurotransmitter in vertebrates, cannot follow transients in intact neural circuits. To develop …
Magnetic resonance imaging for the diagnosis of Parkinson's disease
B Heim, F Krismer, R De Marzi, K Seppi - Journal of neural transmission, 2017 - Springer
The differential diagnosis of parkinsonian syndromes is considered one of the most
challenging in neurology and error rates in the clinical diagnosis can be high even at …
challenging in neurology and error rates in the clinical diagnosis can be high even at …
The sinister face of heme oxygenase-1 in brain aging and disease
Under stressful conditions, cellular heme catabolism to carbon monoxide, iron and biliverdin
is mediated by the 32 kDa enzyme, heme oxygenase-1 (HO-1). A wide range of pro-oxidant …
is mediated by the 32 kDa enzyme, heme oxygenase-1 (HO-1). A wide range of pro-oxidant …
Big GABA: Edited MR spectroscopy at 24 research sites
M Mikkelsen, PB Barker, PK Bhattacharyya, MK Brix… - Neuroimage, 2017 - Elsevier
Magnetic resonance spectroscopy (MRS) is the only biomedical imaging method that can
noninvasively detect endogenous signals from the neurotransmitter γ-aminobutyric acid …
noninvasively detect endogenous signals from the neurotransmitter γ-aminobutyric acid …
Magnetic resonance spectroscopy to assess neuroinflammation and neuropathic pain
Proton magnetic resonance spectroscopy (1 H MRS) has been applied to numerous clinical
studies, especially for neurological disorders. This technique can non-invasively evaluate …
studies, especially for neurological disorders. This technique can non-invasively evaluate …
Short-term monocular deprivation alters GABA in the adult human visual cortex
Neuroplasticity is a fundamental property of the nervous system that is maximal early in life,
within the critical period [1–3]. Resting GABAergic inhibition is necessary to trigger ocular …
within the critical period [1–3]. Resting GABAergic inhibition is necessary to trigger ocular …
Neural control of walking in people with parkinsonism
DS Peterson, FB Horak - Physiology, 2016 - journals.physiology.org
People with Parkinson's disease exhibit debilitating gait impairments, including gait
slowness, increased step variability, and poor postural control. A widespread supraspinal …
slowness, increased step variability, and poor postural control. A widespread supraspinal …
MRI at 7 Tesla and above: demonstrated and potential capabilities
O Kraff, A Fischer, AM Nagel… - Journal of Magnetic …, 2015 - Wiley Online Library
With more than 40 installed MR systems worldwide operating at 7 Tesla or higher, ultra‐high‐
field (UHF) imaging has been established as a platform for clinically oriented research in …
field (UHF) imaging has been established as a platform for clinically oriented research in …